2ops
From Proteopedia
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[[Image:2ops.png|left|200px]] | [[Image:2ops.png|left|200px]] | ||
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{{STRUCTURE_2ops| PDB=2ops | SCENE= }} | {{STRUCTURE_2ops| PDB=2ops | SCENE= }} | ||
===Crystal Structure of Y188C Mutant HIV-1 Reverse Transcriptase in Complex with GW420867X.=== | ===Crystal Structure of Y188C Mutant HIV-1 Reverse Transcriptase in Complex with GW420867X.=== | ||
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{{ABSTRACT_PUBMED_17441703}} | {{ABSTRACT_PUBMED_17441703}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[2ops]] is a 2 chain structure of [[Reverse transcriptase]] with sequence from [http://en.wikipedia.org/wiki/Hiv-1_m:b_hxb2r Hiv-1 m:b_hxb2r]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OPS OCA]. | + | [[2ops]] is a 2 chain structure of [[Reverse transcriptase]] and [[SARS Coronavirus Main Proteinase]] with sequence from [http://en.wikipedia.org/wiki/Hiv-1_m:b_hxb2r Hiv-1 m:b_hxb2r]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OPS OCA]. |
==See Also== | ==See Also== | ||
| - | *[[Reverse transcriptase]] | + | *[[Reverse transcriptase|Reverse transcriptase]] |
| + | *[[SARS Coronavirus Main Proteinase|SARS Coronavirus Main Proteinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017441703</ref><references group="xtra"/> |
[[Category: Hiv-1 m:b_hxb2r]] | [[Category: Hiv-1 m:b_hxb2r]] | ||
[[Category: RNA-directed DNA polymerase]] | [[Category: RNA-directed DNA polymerase]] | ||
Revision as of 15:46, 26 July 2012
Contents |
Crystal Structure of Y188C Mutant HIV-1 Reverse Transcriptase in Complex with GW420867X.
Template:ABSTRACT PUBMED 17441703
About this Structure
2ops is a 2 chain structure of Reverse transcriptase and SARS Coronavirus Main Proteinase with sequence from Hiv-1 m:b_hxb2r. Full crystallographic information is available from OCA.
See Also
Reference
- Ren J, Nichols CE, Chamberlain PP, Weaver KL, Short SA, Chan JH, Kleim JP, Stammers DK. Relationship of potency and resilience to drug resistant mutations for GW420867X revealed by crystal structures of inhibitor complexes for wild-type, Leu100Ile, Lys101Glu, and Tyr188Cys mutant HIV-1 reverse transcriptases. J Med Chem. 2007 May 17;50(10):2301-9. Epub 2007 Apr 19. PMID:17441703 doi:http://dx.doi.org/10.1021/jm061117m
