1zgv
From Proteopedia
(Difference between revisions)
m (Protected "1zgv" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
[[Image:1zgv.png|left|200px]] | [[Image:1zgv.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_1zgv", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_1zgv| PDB=1zgv | SCENE= }} | {{STRUCTURE_1zgv| PDB=1zgv | SCENE= }} | ||
===Thrombin in complex with an oxazolopyridine inhibitor 2=== | ===Thrombin in complex with an oxazolopyridine inhibitor 2=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_16137886}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 16137886 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_16137886}} | {{ABSTRACT_PUBMED_16137886}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[1zgv]] is a 2 chain structure of [[Hirudin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZGV OCA]. | + | [[1zgv]] is a 2 chain structure of [[Hirudin]] and [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZGV OCA]. |
==See Also== | ==See Also== | ||
| - | *[[Hirudin]] | + | *[[Hirudin|Hirudin]] |
| + | *[[Thrombin|Thrombin]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016137886</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Thrombin]] | [[Category: Thrombin]] | ||
| Line 42: | Line 32: | ||
[[Category: Williams, P D.]] | [[Category: Williams, P D.]] | ||
[[Category: Yan, Y.]] | [[Category: Yan, Y.]] | ||
| - | [[Category: Hydrolase | + | [[Category: Hydrolase-hydrolase inhibitor complex]] |
[[Category: Thrombin]] | [[Category: Thrombin]] | ||
[[Category: Thrombin inhibitor complex]] | [[Category: Thrombin inhibitor complex]] | ||
Revision as of 16:04, 26 July 2012
Contents |
Thrombin in complex with an oxazolopyridine inhibitor 2
Template:ABSTRACT PUBMED 16137886
About this Structure
1zgv is a 2 chain structure of Hirudin and Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Deng JZ, McMasters DR, Rabbat PM, Williams PD, Coburn CA, Yan Y, Kuo LC, Lewis SD, Lucas BJ, Krueger JA, Strulovici B, Vacca JP, Lyle TA, Burgey CS. Development of an oxazolopyridine series of dual thrombin/factor Xa inhibitors via structure-guided lead optimization. Bioorg Med Chem Lett. 2005 Oct 15;15(20):4411-6. PMID:16137886 doi:http://dx.doi.org/10.1016/j.bmcl.2005.07.022
Categories: Homo sapiens | Thrombin | Burgey, C S. | Coburn, C A. | Deng, J Z. | Krueger, J A. | Kuo, L C. | Lewis, S D. | Lucas, B J. | Lyle, T A. | McMasters, D R. | Rabbat, P M. | Strulovici, B. | Vacca, J P. | Williams, P D. | Yan, Y. | Hydrolase-hydrolase inhibitor complex | Thrombin inhibitor complex
