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2nnx
From Proteopedia
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[[Image:2nnx.png|left|200px]] | [[Image:2nnx.png|left|200px]] | ||
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{{STRUCTURE_2nnx| PDB=2nnx | SCENE= }} | {{STRUCTURE_2nnx| PDB=2nnx | SCENE= }} | ||
===Crystal Structure of the H46R, H48Q double mutant of human [Cu-Zn] Superoxide Dismutase=== | ===Crystal Structure of the H46R, H48Q double mutant of human [Cu-Zn] Superoxide Dismutase=== | ||
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==See Also== | ==See Also== | ||
| - | *[[Superoxide Dismutase]] | + | *[[Superoxide Dismutase|Superoxide Dismutase]] |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017092942</ref><ref group="xtra">PMID:019227972</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Superoxide dismutase]] | [[Category: Superoxide dismutase]] | ||
Revision as of 12:57, 25 July 2012
Contents |
Crystal Structure of the H46R, H48Q double mutant of human [Cu-Zn] Superoxide Dismutase
Template:ABSTRACT PUBMED 17092942
About this Structure
2nnx is a 4 chain structure of Superoxide Dismutase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Wang J, Caruano-Yzermans A, Rodriguez A, Scheurmann JP, Slunt HH, Cao X, Gitlin J, Hart PJ, Borchelt DR. Disease-associated mutations at copper ligand histidine residues of superoxide dismutase 1 diminish the binding of copper and compromise dimer stability. J Biol Chem. 2007 Jan 5;282(1):345-52. Epub 2006 Nov 8. PMID:17092942 doi:10.1074/jbc.M604503200
- Winkler DD, Schuermann JP, Cao X, Holloway SP, Borchelt DR, Carroll MC, Proescher JB, Culotta VC, Hart PJ. Structural and biophysical properties of the pathogenic SOD1 variant H46R/H48Q. Biochemistry. 2009 Apr 21;48(15):3436-47. PMID:19227972 doi:10.1021/bi8021735
