1ikv

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	==Reference==		==Reference==
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	[[Category: Human immunodeficiency virus 1]]		[[Category: Human immunodeficiency virus 1]]
	[[Category: RNA-directed DNA polymerase]]		[[Category: RNA-directed DNA polymerase]]

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Revision as of 05:42, 31 August 2011

Template:STRUCTURE 1ikv

Contents 1 K103N Mutant HIV-1 Reverse Transcriptase in Complex with Efivarenz 2 About this Structure 3 See Also 4 Reference

K103N Mutant HIV-1 Reverse Transcriptase in Complex with Efivarenz

Template:ABSTRACT PUBMED 11895437

About this Structure

1ikv is a 2 chain structure of Reverse transcriptase with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

See Also

• Reverse transcriptase

Reference

• Lindberg J, Sigurdsson S, Lowgren S, Andersson HO, Sahlberg C, Noreen R, Fridborg K, Zhang H, Unge T. Structural basis for the inhibitory efficacy of efavirenz (DMP-266), MSC194 and PNU142721 towards the HIV-1 RT K103N mutant. Eur J Biochem. 2002 Mar;269(6):1670-7. PMID:11895437
• Udier-Blagovic M, Tirado-Rives J, Jorgensen WL. Structural and energetic analyses of the effects of the K103N mutation of HIV-1 reverse transcriptase on efavirenz analogues. J Med Chem. 2004 Apr 22;47(9):2389-92. PMID:15084137 doi:10.1021/jm0303507