2bt0
From Proteopedia
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[[Image:2bt0.png|left|200px]] | [[Image:2bt0.png|left|200px]] | ||
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{{STRUCTURE_2bt0| PDB=2bt0 | SCENE= }} | {{STRUCTURE_2bt0| PDB=2bt0 | SCENE= }} | ||
===NOVEL, POTENT SMALL MOLECULE INHIBITORS OF THE MOLECULAR CHAPERONE HSP90 DISCOVERED THROUGH STRUCTURE-BASED DESIGN=== | ===NOVEL, POTENT SMALL MOLECULE INHIBITORS OF THE MOLECULAR CHAPERONE HSP90 DISCOVERED THROUGH STRUCTURE-BASED DESIGN=== | ||
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==See Also== | ==See Also== | ||
- | *[[Heat Shock Proteins]] | + | *[[Heat Shock Proteins|Heat Shock Proteins]] |
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:015974572</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Barril, X.]] | [[Category: Barril, X.]] |
Revision as of 10:22, 26 July 2012
Contents |
NOVEL, POTENT SMALL MOLECULE INHIBITORS OF THE MOLECULAR CHAPERONE HSP90 DISCOVERED THROUGH STRUCTURE-BASED DESIGN
Template:ABSTRACT PUBMED 15974572
About this Structure
2bt0 is a 2 chain structure of Heat Shock Proteins with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Dymock BW, Barril X, Brough PA, Cansfield JE, Massey A, McDonald E, Hubbard RE, Surgenor A, Roughley SD, Webb P, Workman P, Wright L, Drysdale MJ. Novel, potent small-molecule inhibitors of the molecular chaperone Hsp90 discovered through structure-based design. J Med Chem. 2005 Jun 30;48(13):4212-5. PMID:15974572 doi:10.1021/jm050355z