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2vku
From Proteopedia
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[[Image:2vku.png|left|200px]] | [[Image:2vku.png|left|200px]] | ||
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{{STRUCTURE_2vku| PDB=2vku | SCENE= }} | {{STRUCTURE_2vku| PDB=2vku | SCENE= }} | ||
===4,4'-DIHYDROXYBENZOPHENONE MIMICS STEROL SUBSTRATE IN THE BINDING SITE OF STEROL 14ALPHA-DEMETHYLASE (CYP51) IN THE X-RAY STRUCTURE OF THE COMPLEX=== | ===4,4'-DIHYDROXYBENZOPHENONE MIMICS STEROL SUBSTRATE IN THE BINDING SITE OF STEROL 14ALPHA-DEMETHYLASE (CYP51) IN THE X-RAY STRUCTURE OF THE COMPLEX=== | ||
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{{ABSTRACT_PUBMED_18367444}} | {{ABSTRACT_PUBMED_18367444}} | ||
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==See Also== | ==See Also== | ||
| - | *[[Cytochrome P450]] | + | *[[Cytochrome P450|Cytochrome P450]] |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018367444</ref><references group="xtra"/> |
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
[[Category: Sterol 14-demethylase]] | [[Category: Sterol 14-demethylase]] | ||
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[[Category: Alpha-beta]] | [[Category: Alpha-beta]] | ||
[[Category: Cyp51-4]] | [[Category: Cyp51-4]] | ||
| - | [[Category: Cytoplasm]] | ||
[[Category: Heme]] | [[Category: Heme]] | ||
[[Category: Heme co-factor]] | [[Category: Heme co-factor]] | ||
Revision as of 13:24, 25 July 2012
Contents |
4,4'-DIHYDROXYBENZOPHENONE MIMICS STEROL SUBSTRATE IN THE BINDING SITE OF STEROL 14ALPHA-DEMETHYLASE (CYP51) IN THE X-RAY STRUCTURE OF THE COMPLEX
Template:ABSTRACT PUBMED 18367444
About this Structure
2vku is a 1 chain structure of Cytochrome P450 with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.
See Also
Reference
- Eddine AN, von Kries JP, Podust MV, Warrier T, Kaufmann SH, Podust LM. X-ray structure of 4,4'-dihydroxybenzophenone mimicking sterol substrate in the active site of sterol 14alpha-demethylase (CYP51). J Biol Chem. 2008 May 30;283(22):15152-9. Epub 2008 Mar 26. PMID:18367444 doi:10.1074/jbc.M801145200
Categories: Mycobacterium tuberculosis | Sterol 14-demethylase | Eddine, A N. | Kries, J P.Von. | Podust, L M. | Podust, M V. | 4'-dihydroxybenzophenone complex | Alpha-beta | Cyp51-4 | Heme | Heme co-factor | Iron | Lipid synthesis | Metal-binding | Monooxygenase | Nadp | Oxidoreductase | Steroid biosynthesis | Sterol biosynthesis
