2q2z

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Revision as of 00:49, 27 December 2010

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Template:STRUCTURE 2q2z

Contents 1 Crystal Structure of KSP in Complex with Inhibitor 22 2 About this Structure 3 See Also 4 Reference

Crystal Structure of KSP in Complex with Inhibitor 22

Template:ABSTRACT PUBMED 17766111

About this Structure

2q2z is a 2 chain structure of Kinesin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Kinesin

Reference

• Roecker AJ, Coleman PJ, Mercer SP, Schreier JD, Buser CA, Walsh ES, Hamilton K, Lobell RB, Tao W, Diehl RE, South VJ, Davide JP, Kohl NE, Yan Y, Kuo LC, Li C, Fernandez-Metzler C, Mahan EA, Prueksaritanont T, Hartman GD. Kinesin spindle protein (KSP) inhibitors. Part 8: Design and synthesis of 1,4-diaryl-4,5-dihydropyrazoles as potent inhibitors of the mitotic kinesin KSP. Bioorg Med Chem Lett. 2007 Oct 15;17(20):5677-82. Epub 2007 Aug 21. PMID:17766111 doi:10.1016/j.bmcl.2007.07.074