2zi2
From Proteopedia
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{{STRUCTURE_2zi2| PDB=2zi2 | SCENE= }} | {{STRUCTURE_2zi2| PDB=2zi2 | SCENE= }} | ||
===Thrombin Inhibition=== | ===Thrombin Inhibition=== | ||
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{{ABSTRACT_PUBMED_20156458}} | {{ABSTRACT_PUBMED_20156458}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[2zi2]] is a 3 chain structure of [[Hirudin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZI2 OCA]. | + | [[2zi2]] is a 3 chain structure of [[Hirudin]] and [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZI2 OCA]. |
==See Also== | ==See Also== | ||
| - | *[[Hirudin]] | + | *[[Hirudin|Hirudin]] |
| + | *[[Thrombin|Thrombin]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020156458</ref><references group="xtra"/> |
| + | [[Category: Hirudo medicinalis]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Thrombin]] | [[Category: Thrombin]] | ||
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[[Category: Klebe, G.]] | [[Category: Klebe, G.]] | ||
[[Category: Acute phase]] | [[Category: Acute phase]] | ||
| - | [[Category: Blood clotting | + | [[Category: Blood clotting]] |
| - | + | ||
[[Category: Blood coagulation]] | [[Category: Blood coagulation]] | ||
| - | [[Category: Calcium]] | ||
[[Category: Cleavage on pair of basic residue]] | [[Category: Cleavage on pair of basic residue]] | ||
[[Category: Disease mutation]] | [[Category: Disease mutation]] | ||
[[Category: Gamma-carboxyglutamic acid]] | [[Category: Gamma-carboxyglutamic acid]] | ||
[[Category: Glycoprotein]] | [[Category: Glycoprotein]] | ||
| + | [[Category: Hydrolase inhibitor]] | ||
| + | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
[[Category: Kringle]] | [[Category: Kringle]] | ||
| - | [[Category: Pharmaceutical]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Secreted]] | [[Category: Secreted]] | ||
[[Category: Serine protease]] | [[Category: Serine protease]] | ||
| - | [[Category: Zymogen]] | ||
Revision as of 03:49, 26 July 2012
Contents |
Thrombin Inhibition
Template:ABSTRACT PUBMED 20156458
About this Structure
2zi2 is a 3 chain structure of Hirudin and Thrombin with sequence from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Baum B, Muley L, Smolinski M, Heine A, Hangauer D, Klebe G. Non-additivity of functional group contributions in protein-ligand binding: a comprehensive study by crystallography and isothermal titration calorimetry. J Mol Biol. 2010 Apr 9;397(4):1042-54. Epub 2010 Feb 12. PMID:20156458 doi:10.1016/j.jmb.2010.02.007
Categories: Hirudo medicinalis | Homo sapiens | Thrombin | Baum, B. | Heine, A. | Klebe, G. | Acute phase | Blood clotting | Blood coagulation | Cleavage on pair of basic residue | Disease mutation | Gamma-carboxyglutamic acid | Glycoprotein | Hydrolase inhibitor | Hydrolase-hydrolase inhibitor complex | Kringle | Protease | Secreted | Serine protease
