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3irx

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[[Image:3irx.png|left|200px]]
[[Image:3irx.png|left|200px]]
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{{STRUCTURE_3irx| PDB=3irx | SCENE= }}
{{STRUCTURE_3irx| PDB=3irx | SCENE= }}
===Crystal Structure of HIV-1 reverse transcriptase (RT) in complex with the Non-nucleoside RT Inhibitor (E)-S-Methyl 5-(1-(3,7-Dimethyl-2-oxo-2,3-dihydrobenzo[d]oxazol-5-yl)-5-(5-methyl-1,3,4-oxadiazol-2-yl)pent-1-enyl)-2-methoxy-3-methylbenzothioate.===
===Crystal Structure of HIV-1 reverse transcriptase (RT) in complex with the Non-nucleoside RT Inhibitor (E)-S-Methyl 5-(1-(3,7-Dimethyl-2-oxo-2,3-dihydrobenzo[d]oxazol-5-yl)-5-(5-methyl-1,3,4-oxadiazol-2-yl)pent-1-enyl)-2-methoxy-3-methylbenzothioate.===
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{{ABSTRACT_PUBMED_19775161}}
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==See Also==
==See Also==
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*[[Reverse transcriptase]]
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*[[Reverse transcriptase|Reverse transcriptase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:19775161</ref><references group="xtra"/>
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<ref group="xtra">PMID:019775161</ref><references group="xtra"/>
[[Category: Human immunodeficiency virus type 1 bh10]]
[[Category: Human immunodeficiency virus type 1 bh10]]
[[Category: Arnold, E.]]
[[Category: Arnold, E.]]
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[[Category: Aspartyl protease]]
[[Category: Aspartyl protease]]
[[Category: Cell membrane]]
[[Category: Cell membrane]]
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[[Category: Cytoplasm]]
 
[[Category: Dna integration]]
[[Category: Dna integration]]
[[Category: Dna recombination]]
[[Category: Dna recombination]]
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[[Category: Viral nucleoprotein]]
[[Category: Viral nucleoprotein]]
[[Category: Virion]]
[[Category: Virion]]
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[[Category: Zinc]]
 
[[Category: Zinc-finger]]
[[Category: Zinc-finger]]

Revision as of 13:43, 25 July 2012

Image:3irx.png

Template:STRUCTURE 3irx

Contents

Crystal Structure of HIV-1 reverse transcriptase (RT) in complex with the Non-nucleoside RT Inhibitor (E)-S-Methyl 5-(1-(3,7-Dimethyl-2-oxo-2,3-dihydrobenzo[d]oxazol-5-yl)-5-(5-methyl-1,3,4-oxadiazol-2-yl)pent-1-enyl)-2-methoxy-3-methylbenzothioate.

Template:ABSTRACT PUBMED 19775161

About this Structure

3irx is a 2 chain structure of Reverse transcriptase with sequence from Human immunodeficiency virus type 1 bh10. Full crystallographic information is available from OCA.

See Also

Reference

  • Cullen MD, Ho WC, Bauman JD, Das K, Arnold E, Hartman TL, Watson KM, Buckheit RW, Pannecouque C, De Clercq E, Cushman M. Crystallographic study of a novel subnanomolar inhibitor provides insight on the binding interactions of alkenyldiarylmethanes with human immunodeficiency virus-1 reverse transcriptase. J Med Chem. 2009 Oct 22;52(20):6467-73. PMID:19775161 doi:10.1021/jm901167t

Proteopedia Page Contributors and Editors (what is this?)

OCA

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