3is9
From Proteopedia
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===Crystal structure of the HIV-1 reverse transcriptase (RT) in complex with the alkenyldiarylmethane (ADAM) Non-nucleoside RT Inhibitor dimethyl 3,3'-(6-methoxy-6-oxohex-1-ene-1,1-diyl)bis(5-cyano-6-methoxybenzoate).=== | ===Crystal structure of the HIV-1 reverse transcriptase (RT) in complex with the alkenyldiarylmethane (ADAM) Non-nucleoside RT Inhibitor dimethyl 3,3'-(6-methoxy-6-oxohex-1-ene-1,1-diyl)bis(5-cyano-6-methoxybenzoate).=== | ||
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==See Also== | ==See Also== | ||
| - | *[[Reverse transcriptase]] | + | *[[Reverse transcriptase|Reverse transcriptase]] |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019775161</ref><references group="xtra"/> |
[[Category: Human immunodeficiency virus type 1 bh10]] | [[Category: Human immunodeficiency virus type 1 bh10]] | ||
[[Category: Arnold, E.]] | [[Category: Arnold, E.]] | ||
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[[Category: Aspartyl protease]] | [[Category: Aspartyl protease]] | ||
[[Category: Cell membrane]] | [[Category: Cell membrane]] | ||
| - | [[Category: Cytoplasm]] | ||
[[Category: Dna integration]] | [[Category: Dna integration]] | ||
[[Category: Dna recombination]] | [[Category: Dna recombination]] | ||
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[[Category: Viral nucleoprotein]] | [[Category: Viral nucleoprotein]] | ||
[[Category: Virion]] | [[Category: Virion]] | ||
| - | [[Category: Zinc]] | ||
[[Category: Zinc-finger]] | [[Category: Zinc-finger]] | ||
Revision as of 03:55, 26 July 2012
Contents |
Crystal structure of the HIV-1 reverse transcriptase (RT) in complex with the alkenyldiarylmethane (ADAM) Non-nucleoside RT Inhibitor dimethyl 3,3'-(6-methoxy-6-oxohex-1-ene-1,1-diyl)bis(5-cyano-6-methoxybenzoate).
Template:ABSTRACT PUBMED 19775161
About this Structure
3is9 is a 2 chain structure of Reverse transcriptase with sequence from Human immunodeficiency virus type 1 bh10. Full crystallographic information is available from OCA.
See Also
Reference
- Cullen MD, Ho WC, Bauman JD, Das K, Arnold E, Hartman TL, Watson KM, Buckheit RW, Pannecouque C, De Clercq E, Cushman M. Crystallographic study of a novel subnanomolar inhibitor provides insight on the binding interactions of alkenyldiarylmethanes with human immunodeficiency virus-1 reverse transcriptase. J Med Chem. 2009 Oct 22;52(20):6467-73. PMID:19775161 doi:10.1021/jm901167t
Categories: Human immunodeficiency virus type 1 bh10 | Arnold, E. | Bauman, J D. | Das, K. | Ho, W C. | Adam | Aid | Aspartyl protease | Cell membrane | Dna integration | Dna recombination | Dna-directed dna polymerase | Endonuclease | Hiv | Hydrolase | Lipoprotein | Membrane | Metal-binding | Multifunctional enzyme | Myristate | Nnrti | Nonnucleoside inhibitor | Nuclease | Nucleotidyltransferase | Nucleus | P51/p66 | Phosphoprotein | Protease | Rna-binding | Rna-directed dna polymerase | Transferase | Transferase-hydrolase complex | Viral nucleoprotein | Virion | Zinc-finger
