This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3hhm
From Proteopedia
m (Protected "3hhm" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
[[Image:3hhm.png|left|200px]] | [[Image:3hhm.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_3hhm", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_3hhm| PDB=3hhm | SCENE= }} | {{STRUCTURE_3hhm| PDB=3hhm | SCENE= }} | ||
===Crystal structure of p110alpha H1047R mutant in complex with niSH2 of p85alpha and the drug wortmannin=== | ===Crystal structure of p110alpha H1047R mutant in complex with niSH2 of p85alpha and the drug wortmannin=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_19805105}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 19805105 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_19805105}} | {{ABSTRACT_PUBMED_19805105}} | ||
| Line 22: | Line 11: | ||
==See Also== | ==See Also== | ||
| - | *[[Phosphoinositide 3-Kinases]] | + | *[[Phosphoinositide 3-Kinases|Phosphoinositide 3-Kinases]] |
| + | *[[The Structure of PI3K|The Structure of PI3K]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019805105</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Phosphatidylinositol-4,5-bisphosphate 3-kinase]] | [[Category: Phosphatidylinositol-4,5-bisphosphate 3-kinase]] | ||
| Line 45: | Line 35: | ||
[[Category: Pi3kca]] | [[Category: Pi3kca]] | ||
[[Category: Pik3r1]] | [[Category: Pik3r1]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
| - | [[Category: Transferase | + | [[Category: Transferase-oncoprotein complex]] |
[[Category: Wortmannin]] | [[Category: Wortmannin]] | ||
Revision as of 07:56, 27 July 2012
Contents |
Crystal structure of p110alpha H1047R mutant in complex with niSH2 of p85alpha and the drug wortmannin
Template:ABSTRACT PUBMED 19805105
About this Structure
3hhm is a 2 chain structure of Phosphoinositide 3-Kinases with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Mandelker D, Gabelli SB, Schmidt-Kittler O, Zhu J, Cheong I, Huang CH, Kinzler KW, Vogelstein B, Amzel LM. A frequent kinase domain mutation that changes the interaction between PI3Kalpha and the membrane. Proc Natl Acad Sci U S A. 2009 Oct 6;106(40):16996-7001. Epub 2009 Sep 23. PMID:19805105
Categories: Homo sapiens | Phosphatidylinositol-4,5-bisphosphate 3-kinase | Amzel, L M. | Gabelli, S B. | Mandelker, D. | Vogelstein, B. | 5-triphosphate | Atp-binding | Disease mutation | H1047r | Kinase | Nucleotide-binding | Oncogene | P110 | P85 | Phosphatidilynositol 3 | Pi3k | Pi3kca | Pik3r1 | Transferase | Transferase-oncoprotein complex | Wortmannin
