This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1smi
From Proteopedia
(Difference between revisions)
m (Protected "1smi" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
[[Image:1smi.png|left|200px]] | [[Image:1smi.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_1smi", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_1smi| PDB=1smi | SCENE= }} | {{STRUCTURE_1smi| PDB=1smi | SCENE= }} | ||
===A single mutation of P450 BM3 induces the conformational rearrangement seen upon substrate-binding in wild-type enzyme=== | ===A single mutation of P450 BM3 induces the conformational rearrangement seen upon substrate-binding in wild-type enzyme=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_15020590}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 15020590 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_15020590}} | {{ABSTRACT_PUBMED_15020590}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[1smi]] is a 2 chain structure of [[Cytochrome P450]] with sequence from [http://en.wikipedia.org/wiki/Bacillus_megaterium Bacillus megaterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SMI OCA]. | + | [[1smi]] is a 2 chain structure of [[NADPH-Cytochrome P450 Reductase]] with sequence from [http://en.wikipedia.org/wiki/Bacillus_megaterium Bacillus megaterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SMI OCA]. |
==See Also== | ==See Also== | ||
| - | *[[Cytochrome P450]] | + | *[[NADPH-Cytochrome P450 Reductase|NADPH-Cytochrome P450 Reductase]] |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:015020590</ref><references group="xtra"/> |
[[Category: Bacillus megaterium]] | [[Category: Bacillus megaterium]] | ||
[[Category: Unspecific monooxygenase]] | [[Category: Unspecific monooxygenase]] | ||
Revision as of 14:08, 25 July 2012
Contents |
A single mutation of P450 BM3 induces the conformational rearrangement seen upon substrate-binding in wild-type enzyme
Template:ABSTRACT PUBMED 15020590
About this Structure
1smi is a 2 chain structure of NADPH-Cytochrome P450 Reductase with sequence from Bacillus megaterium. Full crystallographic information is available from OCA.
See Also
Reference
- Joyce MG, Girvan HM, Munro AW, Leys D. A single mutation in cytochrome P450 BM3 induces the conformational rearrangement seen upon substrate binding in the wild-type enzyme. J Biol Chem. 2004 May 28;279(22):23287-93. Epub 2004 Mar 12. PMID:15020590 doi:http://dx.doi.org/10.1074/jbc.M401717200
