3iu3

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[[Image:3iu3.png|left|200px]]
[[Image:3iu3.png|left|200px]]
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{{STRUCTURE_3iu3| PDB=3iu3 | SCENE= }}
{{STRUCTURE_3iu3| PDB=3iu3 | SCENE= }}
===Crystal structure of the Fab fragment of therapeutic antibody Basiliximab in complex with IL-2Ra (CD25) ectodomain===
===Crystal structure of the Fab fragment of therapeutic antibody Basiliximab in complex with IL-2Ra (CD25) ectodomain===
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{{ABSTRACT_PUBMED_20032294}}
{{ABSTRACT_PUBMED_20032294}}
==About this Structure==
==About this Structure==
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[[3iu3]] is a 9 chain structure of [[Monoclonal Antibody]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IU3 OCA].
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[[3iu3]] is a 9 chain structure of [[Antibody]] and [[Interleukin receptor]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IU3 OCA].
==See Also==
==See Also==
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*[[Monoclonal Antibody]]
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*[[Antibody|Antibody]]
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*[[Interleukin receptor|Interleukin receptor]]
==Reference==
==Reference==
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<ref group="xtra">PMID:20032294</ref><references group="xtra"/>
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<ref group="xtra">PMID:020032294</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Ding, J.]]
[[Category: Ding, J.]]
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[[Category: Immune system]]
[[Category: Immune system]]
[[Category: Membrane]]
[[Category: Membrane]]
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[[Category: Polymorphism]]
 
[[Category: Receptor]]
[[Category: Receptor]]
[[Category: Simulect]]
[[Category: Simulect]]

Revision as of 14:41, 27 July 2012

Image:3iu3.png

Template:STRUCTURE 3iu3

Contents

Crystal structure of the Fab fragment of therapeutic antibody Basiliximab in complex with IL-2Ra (CD25) ectodomain

Template:ABSTRACT PUBMED 20032294

About this Structure

3iu3 is a 9 chain structure of Antibody and Interleukin receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Du J, Yang H, Zhang D, Wang J, Guo H, Peng B, Guo Y, Ding J. Structural basis for the blockage of IL-2 signaling by therapeutic antibody basiliximab. J Immunol. 2010 Feb 1;184(3):1361-8. Epub 2009 Dec 23. PMID:20032294 doi:10.4049/jimmunol.0903178

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