1u4n
From Proteopedia
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[[Image:1u4n.png|left|200px]] | [[Image:1u4n.png|left|200px]] | ||
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{{STRUCTURE_1u4n| PDB=1u4n | SCENE= }} | {{STRUCTURE_1u4n| PDB=1u4n | SCENE= }} | ||
===Crystal Structure Analysis of the M211S/R215L EST2 mutant=== | ===Crystal Structure Analysis of the M211S/R215L EST2 mutant=== | ||
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==See Also== | ==See Also== | ||
- | *[[Lipase]] | + | *[[Carboxylesterase|Carboxylesterase]] |
+ | *[[Lipase|Lipase]] | ||
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:015381425</ref><ref group="xtra">PMID:011061974</ref><ref group="xtra">PMID:014617621</ref><references group="xtra"/> |
[[Category: Alicyclobacillus acidocaldarius]] | [[Category: Alicyclobacillus acidocaldarius]] | ||
[[Category: Carboxylesterase]] | [[Category: Carboxylesterase]] |
Revision as of 14:21, 25 July 2012
Contents |
Crystal Structure Analysis of the M211S/R215L EST2 mutant
Template:ABSTRACT PUBMED 15381425
About this Structure
1u4n is a 1 chain structure of Lipase with sequence from Alicyclobacillus acidocaldarius. Full crystallographic information is available from OCA.
See Also
Reference
- De Simone G, Menchise V, Alterio V, Mandrich L, Rossi M, Manco G, Pedone C. The crystal structure of an EST2 mutant unveils structural insights on the H group of the carboxylesterase/lipase family. J Mol Biol. 2004 Oct 8;343(1):137-46. PMID:15381425 doi:10.1016/j.jmb.2004.08.014
- De Simone G, Galdiero S, Manco G, Lang D, Rossi M, Pedone C. A snapshot of a transition state analogue of a novel thermophilic esterase belonging to the subfamily of mammalian hormone-sensitive lipase. J Mol Biol. 2000 Nov 10;303(5):761-71. PMID:11061974 doi:10.1006/jmbi.2000.4195
- De Simone G, Mandrich L, Menchise V, Giordano V, Febbraio F, Rossi M, Pedone C, Manco G. A substrate-induced switch in the reaction mechanism of a thermophilic esterase: kinetic evidences and structural basis. J Biol Chem. 2004 Feb 20;279(8):6815-23. Epub 2003 Nov 15. PMID:14617621 doi:10.1074/jbc.M307738200