This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1u4n
From Proteopedia
(Difference between revisions)
m (Protected "1u4n" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
[[Image:1u4n.png|left|200px]] | [[Image:1u4n.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_1u4n", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_1u4n| PDB=1u4n | SCENE= }} | {{STRUCTURE_1u4n| PDB=1u4n | SCENE= }} | ||
===Crystal Structure Analysis of the M211S/R215L EST2 mutant=== | ===Crystal Structure Analysis of the M211S/R215L EST2 mutant=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_15381425}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 15381425 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_15381425}} | {{ABSTRACT_PUBMED_15381425}} | ||
| Line 22: | Line 11: | ||
==See Also== | ==See Also== | ||
| - | *[[Lipase]] | + | *[[Carboxylesterase|Carboxylesterase]] |
| + | *[[Lipase|Lipase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:015381425</ref><ref group="xtra">PMID:011061974</ref><ref group="xtra">PMID:014617621</ref><references group="xtra"/> |
[[Category: Alicyclobacillus acidocaldarius]] | [[Category: Alicyclobacillus acidocaldarius]] | ||
[[Category: Carboxylesterase]] | [[Category: Carboxylesterase]] | ||
Revision as of 14:21, 25 July 2012
Contents |
Crystal Structure Analysis of the M211S/R215L EST2 mutant
Template:ABSTRACT PUBMED 15381425
About this Structure
1u4n is a 1 chain structure of Lipase with sequence from Alicyclobacillus acidocaldarius. Full crystallographic information is available from OCA.
See Also
Reference
- De Simone G, Menchise V, Alterio V, Mandrich L, Rossi M, Manco G, Pedone C. The crystal structure of an EST2 mutant unveils structural insights on the H group of the carboxylesterase/lipase family. J Mol Biol. 2004 Oct 8;343(1):137-46. PMID:15381425 doi:10.1016/j.jmb.2004.08.014
- De Simone G, Galdiero S, Manco G, Lang D, Rossi M, Pedone C. A snapshot of a transition state analogue of a novel thermophilic esterase belonging to the subfamily of mammalian hormone-sensitive lipase. J Mol Biol. 2000 Nov 10;303(5):761-71. PMID:11061974 doi:10.1006/jmbi.2000.4195
- De Simone G, Mandrich L, Menchise V, Giordano V, Febbraio F, Rossi M, Pedone C, Manco G. A substrate-induced switch in the reaction mechanism of a thermophilic esterase: kinetic evidences and structural basis. J Biol Chem. 2004 Feb 20;279(8):6815-23. Epub 2003 Nov 15. PMID:14617621 doi:10.1074/jbc.M307738200
