2q38

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caption="2q38, resolution 1.95Å" />
caption="2q38, resolution 1.95Å" />
'''Carbonic Anhydrase II in complex with Saccharin at 1.95 Angstrom'''<br />
'''Carbonic Anhydrase II in complex with Saccharin at 1.95 Angstrom'''<br />
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==Disease==
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Known disease associated with this structure: Osteopetrosis, autosomal recessive 3, with renal tubular acidosis OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=611492 611492]]
==About this Structure==
==About this Structure==
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[[Category: Heine, A.]]
[[Category: Heine, A.]]
[[Category: Klebe, G.]]
[[Category: Klebe, G.]]
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[[Category: Wischeler, J.Schulze.]]
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[[Category: Wischeler, J Schulze.]]
[[Category: BEZ]]
[[Category: BEZ]]
[[Category: GOL]]
[[Category: GOL]]
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[[Category: ten stranded twisted beta sheet]]
[[Category: ten stranded twisted beta sheet]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 23 12:57:42 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:35:28 2008''

Revision as of 16:35, 21 February 2008


2q38, resolution 1.95Å

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Carbonic Anhydrase II in complex with Saccharin at 1.95 Angstrom

Disease

Known disease associated with this structure: Osteopetrosis, autosomal recessive 3, with renal tubular acidosis OMIM:[611492]

About this Structure

2Q38 is a Single protein structure of sequence from Homo sapiens with , , , and as ligands. Active as Carbonate dehydratase, with EC number 4.2.1.1 Full crystallographic information is available from OCA.

Reference

Saccharin inhibits carbonic anhydrases: possible explanation for its unpleasant metallic aftertaste., Kohler K, Hillebrecht A, Schulze Wischeler J, Innocenti A, Heine A, Supuran CT, Klebe G, Angew Chem Int Ed Engl. 2007;46(40):7697-9. PMID:17705204

Page seeded by OCA on Thu Feb 21 18:35:28 2008

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