2c93
From Proteopedia
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{{STRUCTURE_2c93| PDB=2c93 | SCENE= }} | {{STRUCTURE_2c93| PDB=2c93 | SCENE= }} | ||
===THROMBIN INHIBITORS=== | ===THROMBIN INHIBITORS=== | ||
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{{ABSTRACT_PUBMED_16480269}} | {{ABSTRACT_PUBMED_16480269}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[2c93]] is a 3 chain structure of [[Hirudin]] with sequence from [http://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C93 OCA]. | + | [[2c93]] is a 3 chain structure of [[Hirudin]] and [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C93 OCA]. |
==See Also== | ==See Also== | ||
| - | *[[Hirudin]] | + | *[[Hirudin|Hirudin]] |
| + | *[[Thrombin|Thrombin]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016480269</ref><references group="xtra"/> |
[[Category: Hirudo medicinalis]] | [[Category: Hirudo medicinalis]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Gamma-carboxyglutamic acid]] | [[Category: Gamma-carboxyglutamic acid]] | ||
[[Category: Glycoprotein]] | [[Category: Glycoprotein]] | ||
| - | [[Category: Hydrolase]] | + | [[Category: Hydrolase-hydrolase inhibitor complex]] |
[[Category: Kringle]] | [[Category: Kringle]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Serine protease]] | [[Category: Serine protease]] | ||
[[Category: Thrombin]] | [[Category: Thrombin]] | ||
Revision as of 15:20, 27 July 2012
Contents |
THROMBIN INHIBITORS
Template:ABSTRACT PUBMED 16480269
About this Structure
2c93 is a 3 chain structure of Hirudin and Thrombin with sequence from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Howard N, Abell C, Blakemore W, Chessari G, Congreve M, Howard S, Jhoti H, Murray CW, Seavers LC, van Montfort RL. Application of fragment screening and fragment linking to the discovery of novel thrombin inhibitors. J Med Chem. 2006 Feb 23;49(4):1346-55. PMID:16480269 doi:10.1021/jm050850v
Categories: Hirudo medicinalis | Homo sapiens | Thrombin | Abell, C. | Blakemore, W. | Carr, R. | Chessari, G. | Congreve, M. | Howard, N. | Howard, S. | Jhoti, H. | Montfort, R L.M Van. | Murray, C W. | Seavers, L C.A. | Blood coagulation | Gamma-carboxyglutamic acid | Glycoprotein | Hydrolase-hydrolase inhibitor complex | Kringle | Protease | Serine protease
