Porin

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[[2xe5]], [[2xe1]], [[2xe2]], [[2xe3]], [[2j1n]] – EcOmpC – ''Escherichia coli''<br />
[[2xe5]], [[2xe1]], [[2xe2]], [[2xe3]], [[2j1n]] – EcOmpC – ''Escherichia coli''<br />
-
[[2j4u]] – EcOmpC+lactotransferrin fragment<br />
 
[[3k19]], [[3k1b]], [[2zfg]], [[1omf]], [[2omf]], [[1opf]] – EcOmpF<br />
[[3k19]], [[3k1b]], [[2zfg]], [[1omf]], [[2omf]], [[1opf]] – EcOmpF<br />
[[1hxt]], [[1hxu]], [[1hxx]], [[1bt9]], [[1gfm]], [[1gfn]], [[1gfo]], [[1gfp]], [[1gfq]], [[1mpf]] – EcOmpF (mutant)<br />
[[1hxt]], [[1hxu]], [[1hxx]], [[1bt9]], [[1gfm]], [[1gfn]], [[1gfo]], [[1gfp]], [[1gfq]], [[1mpf]] – EcOmpF (mutant)<br />
-
[[2zld]] – EcOmpF+colicin E3<br />
 
-
[[3o0e]] - EcOmpF+colicin peptide<br />
 
-
[[3hw9]], [[3hwb]] – EcOmpF+ions<br />
 
-
[[3fyx]] – EcOmpF+dibenzo-18-crown-6<br />
 
[[2iwv]], [[2iww]], [[2f1c]] - EcOmpG<br />
[[2iwv]], [[2iww]], [[2f1c]] - EcOmpG<br />
[[2wjq]], [[2wjr]] – EcOmp NANC<br />
[[2wjq]], [[2wjr]] – EcOmp NANC<br />
-
[[1af6]], [[1mpq]], [[1mpm]], [[1mpn]], [[1mpo]] – EcOmp LAMB+sugars<br />
 
[[1pho]] - EcOmp<br />
[[1pho]] - EcOmp<br />
[[3a2r]] – NmOmpB – ''Neisseria meningitides''<br />
[[3a2r]] – NmOmpB – ''Neisseria meningitides''<br />
-
[[3a2s]], [[3a2t]] – NmOmpB+sugars<br />
 
-
[[3a2u]] - NmOmpB+AMPPNP<br />
 
[[3jty]] – Omp – ''Pseudomonas fluorescens''<br />
[[3jty]] – Omp – ''Pseudomonas fluorescens''<br />
[[2qtk]] – PaOprK – ''Pseudomonas aeruginosa''<br />
[[2qtk]] – PaOprK – ''Pseudomonas aeruginosa''<br />
[[2odj]] - PaOprD<br />
[[2odj]] - PaOprD<br />
-
[[2o4v]] – PaOprP+phosphate<br />
 
[[2v9u]] – MsOmp rim domain – ''Mycobacteria smegmatis''<br />
[[2v9u]] – MsOmp rim domain – ''Mycobacteria smegmatis''<br />
[[1uun]] – MsOmp (mutant)<br />
[[1uun]] – MsOmp (mutant)<br />
-
[[2fgq]] – DaOmp32+malate – ''Delftia acidovorans''<br />
+
[[2fgr]] - DaOmp32 - ''Delftia acidovorans''<br />
-
[[2fgr]] - DaOmp32<br />
+
[[1a0s]], [[1mpr]] - StOmp - ''Salmonella typhimurium''<br />
-
[[1e54]] – Omp32+sulfate – ''Comamonas acidovorans''<br />
+
[[2prn]], [[1bh3]], [[3prn]], [[5prn]], [[6prn]], [[7prn]], [[8prn]] – RbOmp (mutant) - ''Rhodopseudomonas blastica''<br />
-
[[1oh2]], [[1a0t]] – StOmp+sucrose – ''Salmonella typhimurium''<br />
+
-
[[1a0s]], [[1mpr]] - StOmp<br />
+
-
[[1h6s]] – RbOmp+inserted sequence – ''Rhodopseudomonas blastica''<br />
+
-
[[2prn]], [[1bh3]], [[3prn]], [[5prn]], [[6prn]], [[7prn]], [[8prn]] – RbOmp (mutant)<br />
+
[[1prn]] - RbOmp<br />
[[1prn]] - RbOmp<br />
[[1osm]] – OmpK36 – ''Klebsiella pneumoniae''<br />
[[1osm]] – OmpK36 – ''Klebsiella pneumoniae''<br />
[[2por]], [[3por]] – Omp – ''Rhodobacter capsulatus''<br />
[[2por]], [[3por]] – Omp – ''Rhodobacter capsulatus''<br />
 +
 +
==Porin + polypeptides ==
 +
 +
[[2j4u]] - EcOmpC + lactotransferrin fragment<br />
 +
[[2zld]] - EcOmpF + colicin E3<br />
 +
[[3o0e]] - EcOmpF + colicin peptide<br />
 +
[[1h6s]] - RbOmp + inserted sequence
 +
 +
==Porin + various compounds==
 +
 +
[[3hw9]], [[3hwb]] - EcOmpF + ions ,br /.
 +
[[3fyx]] - Ec~OmpF + dibenzo-18-crown-6<br />
 +
[[1af6]], [[1mpq]], [[1mpm]], [[1mpn]], [1mpo]] - EcOmp LAMB + sugars<br />
 +
[[3a2s]], [[3a2t]] - NmOmpB + sugars<br />
 +
[[3a2u]] - NmOmpB + AMPPNP<br />
 +
[[2o4v]] - PaOprP + phosphate<br />
 +
[[2fgq]] - DaOmp32 + malate<br />
 +
[[1e54]] - Omp32 + sulfate - ''Comamonas acidovorans''<br />
 +
[[1oh2]], [[1a0t]] - StOmp + sucrose

Revision as of 09:21, 22 March 2011

Image:Ompc.png
Crystal structure of Porin OmpC from E. coli, 2j1n

PDB ID 2j1n

Drag the structure with the mouse to rotate
Porin OmpC from E. coli, 2j1n
Ligands: , ,
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml


Porin or Outer Membrane Proteins (Omps) act as channels which allow passive diffusion of sugars, ions and amino acids. They are beta barrel proteins which traverse the cell membrane. In E. coli they are named according to their genes: C, F, G (OmpC, OmpF, Ompg). Voltage-Dependent Anion Channel (VDAC) is ion channel Omp found in outer mitochondrial membrane. In Pseudomonas aeruginosa the porin gene products are named OprD, OprK, OprP. The images at the left and at the right correspond to one representative porin structure, i.e. crystal structure osmoporin OmpC from Escherichia coli (2j1n). OmpC has three beta-barrels associated to form a [1].

Contents


Porin

2xe5, 2xe1, 2xe2, 2xe3, 2j1n – EcOmpC – Escherichia coli
3k19, 3k1b, 2zfg, 1omf, 2omf, 1opf – EcOmpF
1hxt, 1hxu, 1hxx, 1bt9, 1gfm, 1gfn, 1gfo, 1gfp, 1gfq, 1mpf – EcOmpF (mutant)
2iwv, 2iww, 2f1c - EcOmpG
2wjq, 2wjr – EcOmp NANC
1pho - EcOmp
3a2r – NmOmpB – Neisseria meningitides
3jty – Omp – Pseudomonas fluorescens
2qtk – PaOprK – Pseudomonas aeruginosa
2odj - PaOprD
2v9u – MsOmp rim domain – Mycobacteria smegmatis
1uun – MsOmp (mutant)
2fgr - DaOmp32 - Delftia acidovorans
1a0s, 1mpr - StOmp - Salmonella typhimurium
2prn, 1bh3, 3prn, 5prn, 6prn, 7prn, 8prn – RbOmp (mutant) - Rhodopseudomonas blastica
1prn - RbOmp
1osm – OmpK36 – Klebsiella pneumoniae
2por, 3por – Omp – Rhodobacter capsulatus

Porin + polypeptides

2j4u - EcOmpC + lactotransferrin fragment
2zld - EcOmpF + colicin E3
3o0e - EcOmpF + colicin peptide
1h6s - RbOmp + inserted sequence

Porin + various compounds

3hw9, 3hwb - EcOmpF + ions ,br /. 3fyx - Ec~OmpF + dibenzo-18-crown-6
1af6, 1mpq, 1mpm, 1mpn, [1mpo]] - EcOmp LAMB + sugars
3a2s, 3a2t - NmOmpB + sugars
3a2u - NmOmpB + AMPPNP
2o4v - PaOprP + phosphate
2fgq - DaOmp32 + malate
1e54 - Omp32 + sulfate - Comamonas acidovorans
1oh2, 1a0t - StOmp + sucrose


Voltage-Dependent Anion Channel

2jk4 – hVDAC-1 – human
2k4t - hVDAC-1 - NMR
3emn – VDAC-1 - mouse

References

  1. ↑ Basle A, Rummel G, Storici P, Rosenbusch JP, Schirmer T. Crystal structure of osmoporin OmpC from E. coli at 2.0 A. J Mol Biol. 2006 Oct 6;362(5):933-42. Epub 2006 Aug 3. PMID:16949612 doi:10.1016/j.jmb.2006.08.002
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