2gqg
From Proteopedia
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[[Image:2gqg.png|left|200px]] | [[Image:2gqg.png|left|200px]] | ||
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{{STRUCTURE_2gqg| PDB=2gqg | SCENE= }} | {{STRUCTURE_2gqg| PDB=2gqg | SCENE= }} | ||
===X-ray Crystal Structure of Dasatinib (BMS-354825) Bound to Activated ABL Kinase Domain=== | ===X-ray Crystal Structure of Dasatinib (BMS-354825) Bound to Activated ABL Kinase Domain=== | ||
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| - | The line below this paragraph, {{ABSTRACT_PUBMED_16740718}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 16740718 is the PubMed ID number. | ||
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{{ABSTRACT_PUBMED_16740718}} | {{ABSTRACT_PUBMED_16740718}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[2gqg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GQG OCA]. | + | [[2gqg]] is a 2 chain structure of [[Proto-oncogene tyrosine-protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GQG OCA]. |
==See Also== | ==See Also== | ||
| - | *[[Dasatinib]] | + | *[[Dasatinib|Dasatinib]] |
| + | *[[Proto-oncogene tyrosine-protein kinase|Proto-oncogene tyrosine-protein kinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016740718</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific protein-tyrosine kinase]] | [[Category: Non-specific protein-tyrosine kinase]] | ||
Revision as of 23:59, 25 July 2012
Contents |
X-ray Crystal Structure of Dasatinib (BMS-354825) Bound to Activated ABL Kinase Domain
Template:ABSTRACT PUBMED 16740718
About this Structure
2gqg is a 2 chain structure of Proto-oncogene tyrosine-protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Tokarski JS, Newitt JA, Chang CY, Cheng JD, Wittekind M, Kiefer SE, Kish K, Lee FY, Borzillerri R, Lombardo LJ, Xie D, Zhang Y, Klei HE. The structure of Dasatinib (BMS-354825) bound to activated ABL kinase domain elucidates its inhibitory activity against imatinib-resistant ABL mutants. Cancer Res. 2006 Jun 1;66(11):5790-7. PMID:16740718 doi:66/11/5790
