This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3kle
From Proteopedia
(Difference between revisions)
| Line 11: | Line 11: | ||
===Crystal structure of AZT-resistant HIV-1 Reverse Transcriptase crosslinked to a DSDNA with a bound excision product, AZTPPPPA=== | ===Crystal structure of AZT-resistant HIV-1 Reverse Transcriptase crosslinked to a DSDNA with a bound excision product, AZTPPPPA=== | ||
| + | |||
| + | <!-- | ||
| + | The line below this paragraph, {{ABSTRACT_PUBMED_20852643}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 20852643 is the PubMed ID number. | ||
| + | --> | ||
| + | {{ABSTRACT_PUBMED_20852643}} | ||
==About this Structure== | ==About this Structure== | ||
| Line 16: | Line 22: | ||
==See Also== | ==See Also== | ||
| + | *[[AZT-resistant HIV-1 reverse transcriptase]] | ||
*[[Phl p 2]] | *[[Phl p 2]] | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:20852643</ref><references group="xtra"/> | ||
[[Category: Human immunodeficiency virus 1]] | [[Category: Human immunodeficiency virus 1]] | ||
[[Category: Arnold, E.]] | [[Category: Arnold, E.]] | ||
| Line 22: | Line 32: | ||
[[Category: Sarafianos, S G.]] | [[Category: Sarafianos, S G.]] | ||
[[Category: Tu, X.]] | [[Category: Tu, X.]] | ||
| - | [[Category: Aid]] | ||
| - | [[Category: Azt]] | ||
| - | [[Category: Azt adenosine dinucleoside tetraphosphate]] | ||
| - | [[Category: Azt resistance mechanism]] | ||
| - | [[Category: Aztp4a]] | ||
| - | [[Category: Aztppppa]] | ||
| - | [[Category: Dna polymerase]] | ||
| - | [[Category: Dna-directed dna polymerase]] | ||
| - | [[Category: Endonuclease]] | ||
| - | [[Category: Hiv]] | ||
| - | [[Category: Hiv-1]] | ||
| - | [[Category: Hydrolase]] | ||
| - | [[Category: Magnesium]] | ||
| - | [[Category: Metal-binding]] | ||
| - | [[Category: Multifunctional enzyme]] | ||
| - | [[Category: Myristate]] | ||
| - | [[Category: Nrti]] | ||
| - | [[Category: Nrti resistance]] | ||
| - | [[Category: Nuclease]] | ||
| - | [[Category: Nucleoside inhibitor]] | ||
| - | [[Category: Nucleotide excision]] | ||
| - | [[Category: P51/p66]] | ||
| - | [[Category: Resistance mutation]] | ||
| - | [[Category: Reverse transcriptase]] | ||
| - | [[Category: Rna-directed dna polymerase]] | ||
| - | [[Category: Rt]] | ||
| - | [[Category: Thymidine analog mutation]] | ||
| - | [[Category: Transferase]] | ||
| - | [[Category: Transferase-dna complex]] | ||
Revision as of 04:38, 12 January 2011
Contents |
Crystal structure of AZT-resistant HIV-1 Reverse Transcriptase crosslinked to a DSDNA with a bound excision product, AZTPPPPA
Template:ABSTRACT PUBMED 20852643
About this Structure
3kle is a 16 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
See Also
Reference
- Tu X, Das K, Han Q, Bauman JD, Clark AD Jr, Hou X, Frenkel YV, Gaffney BL, Jones RA, Boyer PL, Hughes SH, Sarafianos SG, Arnold E. Structural basis of HIV-1 resistance to AZT by excision. Nat Struct Mol Biol. 2010 Oct;17(10):1202-9. Epub 2010 Sep 19. PMID:20852643 doi:10.1038/nsmb.1908
