3pr0

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m (Protected "3pr0" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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[[Image:3pr0.jpg|left|200px]]
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The entry 3pr0 is ON HOLD until Paper Publication
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{{STRUCTURE_3pr0| PDB=3pr0 | SCENE= }}
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Authors: Mileni, M., Han, G.W., Boger, D.L., Stevens. R.C.
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===Crystal Structure of a Covalently Bound alpha-Ketoheterocycle Inhibitor (Phenhexyl/Oxadiazole/Pyridine) to a Humanized Variant of Fatty Acid Amide Hydrolase===
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Description: Crystal Structure of a Covalently Bound alpha-Ketoheterocycle Inhibitor (Phenhexyl/Oxadiazole/Pyridine) to a Humanized Variant of Fatty Acid Amide Hydrolase
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{{ABSTRACT_PUBMED_21355555}}
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==About this Structure==
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[[3pr0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PR0 OCA].
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==Reference==
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<ref group="xtra">PMID:021355555</ref><references group="xtra"/>
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[[Category: Amidase]]
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[[Category: Rattus norvegicus]]
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[[Category: Boger, D L.]]
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[[Category: Han, G W.]]
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[[Category: Mileni, M.]]
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[[Category: Stevens, R C.]]
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[[Category: Alpha-ketoheterocycle]]
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[[Category: Endocannabinoid degradation]]
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[[Category: Faah]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Membrane protein]]
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[[Category: Oxadiazole]]
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[[Category: Protein-inhibitor complex]]

Revision as of 12:15, 16 November 2011

Image:3pr0.jpg

Template:STRUCTURE 3pr0

Crystal Structure of a Covalently Bound alpha-Ketoheterocycle Inhibitor (Phenhexyl/Oxadiazole/Pyridine) to a Humanized Variant of Fatty Acid Amide Hydrolase

Template:ABSTRACT PUBMED 21355555

About this Structure

3pr0 is a 2 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Mileni M, Garfunkle J, Ezzili C, Cravatt BF, Stevens RC, Boger DL. Fluoride-mediated capture of a noncovalent bound state of a reversible covalent enzyme inhibitor: X-ray crystallographic analysis of an exceptionally potent alpha-ketoheterocycle inhibitor of fatty acid amide hydrolase. J Am Chem Soc. 2011 Mar 23;133(11):4092-100. Epub 2011 Feb 28. PMID:21355555 doi:10.1021/ja110877y

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OCA

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