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3kjs

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Revision as of 18:28, 29 December 2010

Image:3kjs.png

Template:STRUCTURE 3kjs

Crystal Structure of T. cruzi DHFR-TS with 3 high affinity DHFR inhibitors: DQ1 inhibitor complex

Template:ABSTRACT PUBMED 20452776

About this Structure

3kjs is a 4 chain structure with sequence from Trypanosoma cruzi. Full crystallographic information is available from OCA.

Reference

  • Schormann N, Velu SE, Murugesan S, Senkovich O, Walker K, Chenna BC, Shinkre B, Desai A, Chattopadhyay D. Synthesis and characterization of potent inhibitors of Trypanosoma cruzi dihydrofolate reductase. Bioorg Med Chem. 2010 Jun 1;18(11):4056-66. Epub 2010 Apr 9. PMID:20452776 doi:10.1016/j.bmc.2010.04.020

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OCA

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