3nox

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	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Klei, H E.]]		[[Category: Klei, H E.]]

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Revision as of 04:40, 27 July 2011

Template:STRUCTURE 3nox

Contents 1 Crystal structure of human DPP-IV in complex with Sa-(+)-(6-(aminomethyl)-5-(2,4-dichlorophenyl)-7-methylimidazo[1,2-a]pyrimidin-2-yl)(morpholino)methanone 2 About this Structure 3 See Also 4 Reference

Crystal structure of human DPP-IV in complex with Sa-(+)-(6-(aminomethyl)-5-(2,4-dichlorophenyl)-7-methylimidazo[1,2-a]pyrimidin-2-yl)(morpholino)methanone

Template:ABSTRACT PUBMED 20684603

About this Structure

3nox is a 2 chain structure of Dipeptidyl peptidase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Dipeptidyl peptidase

Reference

• Meng W, Brigance RP, Chao HJ, Fura A, Harrity T, Marcinkeviciene J, O'Connor SP, Tamura JK, Xie D, Zhang Y, Klei HE, Kish K, Weigelt CA, Turdi H, Wang A, Zahler R, Kirby MS, Hamann LG. Discovery of 6-(Aminomethyl)-5-(2,4-dichlorophenyl)-7-methylimidazo[1,2-a]pyrimidine-2- carboxamides as potent, selective dipeptidyl peptidase-4 (DPP4) inhibitors. J Med Chem. 2010 Aug 12;53(15):5620-8. PMID:20684603 doi:10.1021/jm100634a