2oss

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Revision as of 15:41, 5 January 2011

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Template:STRUCTURE 2oss

Crystal structure of the Bromo domain 1 in human Bromodomain Containing Protein 4 (BRD4)

Template:ABSTRACT PUBMED 20871596

About this Structure

2oss is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Filippakopoulos P, Qi J, Picaud S, Shen Y, Smith WB, Fedorov O, Morse EM, Keates T, Hickman TT, Felletar I, Philpott M, Munro S, McKeown MR, Wang Y, Christie AL, West N, Cameron MJ, Schwartz B, Heightman TD, La Thangue N, French CA, Wiest O, Kung AL, Knapp S, Bradner JE. Selective inhibition of BET bromodomains. Nature. 2010 Sep 24. PMID:20871596 doi:10.1038/nature09504