3p2u

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Template:STRUCTURE 3p2u

Contents 1 Crystal structure of PhnP in complex with orthovanadate 2 Function 3 About this Structure 4 Reference

Crystal structure of PhnP in complex with orthovanadate

Template:ABSTRACT PUBMED 021830807

Function

[PHNP_ECOLI] Catalyzes the hydrolysis of the cyclic ribose-phosphate to form alpha-D-ribose 1,5-bisphosphate.^{[1] [2]}

About this Structure

3p2u is a 2 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

1. ↑ Hove-Jensen B, McSorley FR, Zechel DL. Physiological role of phnP-specified phosphoribosyl cyclic phosphodiesterase in catabolism of organophosphonic acids by the carbon-phosphorus lyase pathway. J Am Chem Soc. 2011 Mar 16;133(10):3617-24. doi: 10.1021/ja1102713. Epub 2011 Feb, 22. PMID:21341651 doi:10.1021/ja1102713
2. ↑ Podzelinska K, He SM, Wathier M, Yakunin A, Proudfoot M, Hove-Jensen B, Zechel DL, Jia Z. Structure of PhnP, a phosphodiesterase of the carbon-phosphorus lyase pathway for phosphonate degradation. J Biol Chem. 2009 Jun 19;284(25):17216-26. Epub 2009 Apr 14. PMID:19366688 doi:10.1074/jbc.M808392200