Leukotriene A4 Hydrolase
From Proteopedia
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[[3fh5]], [[3fh7]], [[3fh8]], [[3fhe]], [[3ftz]], [[3ful]], [[3ftv]], [[3ftw]], [[3fty]], [[3fu0]], [[3fu3]], [[3fu5]], [[3fu6]], [[3fud]], [[3fue]], [[3fuf]], [[3fuh]], [[3fui]], [[3fuj]], [[3fuk]], [[3fum]], [[3fun]], [[3b7r]], [[2r59]], [[3cho]], [[3chp]], [[3chq]], [[3chr]], [[3chs]], [[2vj8]] – hLA4H+inhibitor<br /> | [[3fh5]], [[3fh7]], [[3fh8]], [[3fhe]], [[3ftz]], [[3ful]], [[3ftv]], [[3ftw]], [[3fty]], [[3fu0]], [[3fu3]], [[3fu5]], [[3fu6]], [[3fud]], [[3fue]], [[3fuf]], [[3fuh]], [[3fui]], [[3fuj]], [[3fuk]], [[3fum]], [[3fun]], [[3b7r]], [[2r59]], [[3cho]], [[3chp]], [[3chq]], [[3chr]], [[3chs]], [[2vj8]] – hLA4H+inhibitor<br /> | ||
[[3ftz]], [[3ftv]], [[3ftw]], [[3ftx]], [[3fui]] - hLTA4H+aniline derivative<br /> | [[3ftz]], [[3ftv]], [[3ftw]], [[3ftx]], [[3fui]] - hLTA4H+aniline derivative<br /> | ||
- | [[3fts]], [[3ftu | + | [[3fts]], [[3ftu]], [[3ftx]] - hLTA4H+resveratrol derivative<br /> |
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[[3b7s]], [[3b7t]] - hLTA4H (mutant)+tripeptide<br /> | [[3b7s]], [[3b7t]] - hLTA4H (mutant)+tripeptide<br /> | ||
+ | [[3b7u]] - hLTA4H+kelatorphan<br /> | ||
[[1hs6]] - hLTA4H+bestatin<br /> | [[1hs6]] - hLTA4H+bestatin<br /> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] |
Revision as of 06:19, 13 January 2011
Leukotriene A4 Hydrolase (LTA4H) is an aminopeptidase which converts leukotriene A4 to leukotriene B4 as part of the arachidonic acid metabolism. The images at the left and at the right correspond to one representative LTA4H, i.e. the crystal structure of yeast Leukotriene A4 Hydrolase (2xpz).
3D Structures of Leukotriene A4 Hydrolase
2xpz – yLTA4H – yeast
1xpy – yLTA4H+glutathione
2xq0 – yLTA4H+bestatin
1sqm, 1gw6, 1h19 - hLTA4H (mutant)
3fh5, 3fh7, 3fh8, 3fhe, 3ftz, 3ful, 3ftv, 3ftw, 3fty, 3fu0, 3fu3, 3fu5, 3fu6, 3fud, 3fue, 3fuf, 3fuh, 3fui, 3fuj, 3fuk, 3fum, 3fun, 3b7r, 2r59, 3cho, 3chp, 3chq, 3chr, 3chs, 2vj8 – hLA4H+inhibitor
3ftz, 3ftv, 3ftw, 3ftx, 3fui - hLTA4H+aniline derivative
3fts, 3ftu, 3ftx - hLTA4H+resveratrol derivative
3b7s, 3b7t - hLTA4H (mutant)+tripeptide
3b7u - hLTA4H+kelatorphan
1hs6 - hLTA4H+bestatin