3oq1

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m (Protected "3oq1" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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[[Image:3oq1.jpg|left|200px]]
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The entry 3oq1 is ON HOLD until Paper Publication
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{{STRUCTURE_3oq1| PDB=3oq1 | SCENE= }}
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Authors: Wang, Z., Sudom, A., Walker, N.P.
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===Crystal Structure of 11beta-Hydroxysteroid Dehydrogenase-1 (11b-HSD1) in Complex with Diarylsulfone Inhibitor===
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Description: Crystal Structure of 11beta-Hydroxysteroid Dehydrogenase-1 (11b-HSD1) in Complex with Diarylsulfone Inhibitor
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{{ABSTRACT_PUBMED_20971000}}
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==About this Structure==
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[[3oq1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OQ1 OCA].
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==Reference==
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<ref group="xtra">PMID:020971000</ref><references group="xtra"/>
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[[Category: 11-beta-hydroxysteroid dehydrogenase]]
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[[Category: Homo sapiens]]
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[[Category: Sudom, A.]]
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[[Category: Walker, N P.]]
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[[Category: Wang, Z.]]
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[[Category: Oxidoreductase]]
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[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]

Revision as of 06:37, 20 July 2011

Template:STRUCTURE 3oq1

Crystal Structure of 11beta-Hydroxysteroid Dehydrogenase-1 (11b-HSD1) in Complex with Diarylsulfone Inhibitor

Template:ABSTRACT PUBMED 20971000

About this Structure

3oq1 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Yan X, Wang Z, Sudom A, Cardozo M, DeGraffenreid M, Di Y, Fan P, He X, Jaen JC, Labelle M, Liu J, Ma J, McMinn D, Miao S, Sun D, Tang L, Tu H, Ursu S, Walker N, Ye Q, Powers JP. The synthesis and SAR of novel diarylsulfone 11beta-HSD1 inhibitors. Bioorg Med Chem Lett. 2010 Dec 1;20(23):7071-5. Epub 2010 Sep 29. PMID:20971000 doi:10.1016/j.bmcl.2010.09.097

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