2xpb
From Proteopedia
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| - | [[Image:2xpb. | + | [[Image:2xpb.png|left|200px]] |
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020932746</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Peptidylprolyl isomerase]] | [[Category: Peptidylprolyl isomerase]] | ||
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[[Category: Scrace, S F.]] | [[Category: Scrace, S F.]] | ||
[[Category: Surgenor, A E.]] | [[Category: Surgenor, A E.]] | ||
| + | [[Category: Cell cycle]] | ||
| + | [[Category: Isomerase]] | ||
| + | [[Category: Oncogenic transformation]] | ||
| + | [[Category: Proline directed kinase]] | ||
Revision as of 07:11, 7 December 2011
DISCOVERY OF CELL-ACTIVE PHENYL-IMIDAZOLE PIN1 INHIBITORS BY STRUCTURE-GUIDED FRAGMENT EVOLUTION
Template:ABSTRACT PUBMED 20932746
About this Structure
2xpb is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Potter A, Oldfield V, Nunns C, Fromont C, Ray S, Northfield CJ, Bryant CJ, Scrace SF, Robinson D, Matossova N, Baker L, Dokurno P, Surgenor AE, Davis B, Richardson CM, Murray JB, Moore JD. Discovery of cell-active phenyl-imidazole Pin1 inhibitors by structure-guided fragment evolution. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6483-8. Epub 2010 Sep 17. PMID:20932746 doi:10.1016/j.bmcl.2010.09.063
Categories: Homo sapiens | Peptidylprolyl isomerase | Baker, L. | Bryant, C J. | Davis, B E. | Dokurno, P. | Fromont, C. | Matossova, N. | Moore, J D. | Murray, J B. | Northfield, C J. | Nunns, C. | Oldfield, V. | Potter, A. | Ray, S. | Richardson, C M. | Robinson, D. | Scrace, S F. | Surgenor, A E. | Cell cycle | Isomerase | Oncogenic transformation | Proline directed kinase
