3n7y

From Proteopedia

Revision as of 05:14, 12 January 2011 (edit) OCA (Talk | contribs) ← Previous diff

Revision as of 05:14, 12 January 2011 (edit) (undo) OCA (Talk | contribs) m (Protected "3n7y" [edit=sysop:move=sysop]) Next diff →

---

Revision as of 05:14, 12 January 2011

proteopedia linkproteopedia link

Template:STRUCTURE 3n7y

Crystal Structure of the Grb2 SH2 Domain in Complex with a 20-Membered Macrocyclic Ligand Having the Sequence pYVNV

Template:ABSTRACT PUBMED 21116482

About this Structure

3n7y is a 6 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Delorbe JE, Clements JH, Whiddon BB, Martin SF. Thermodynamic and Structural Effects of Macrocyclization as a Constraining Method in Protein-Ligand Interactions. ACS Med Chem Lett. 2010 Nov 11;1(8):448-452. PMID:21116482 doi:10.1021/ml100142y