3klf

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[[Image:3klf.png|left|200px]]
[[Image:3klf.png|left|200px]]
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{{STRUCTURE_3klf| PDB=3klf | SCENE= }}
{{STRUCTURE_3klf| PDB=3klf | SCENE= }}
===Crystal structure of wild-type HIV-1 Reverse Transcriptase crosslinked to a DSDNA with a bound excision product, AZTPPPPA===
===Crystal structure of wild-type HIV-1 Reverse Transcriptase crosslinked to a DSDNA with a bound excision product, AZTPPPPA===
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{{ABSTRACT_PUBMED_20852643}}
{{ABSTRACT_PUBMED_20852643}}
==About this Structure==
==About this Structure==
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[[3klf]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KLF OCA].
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[[3klf]] is a 16 chain structure of [[Reverse transcriptase]] with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KLF OCA].
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==See Also==
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*[[Reverse transcriptase|Reverse transcriptase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:20852643</ref><references group="xtra"/>
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<ref group="xtra">PMID:020852643</ref><references group="xtra"/>
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Arnold, E.]]
[[Category: Arnold, E.]]
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[[Category: Sarafianos, S G.]]
[[Category: Sarafianos, S G.]]
[[Category: Tu, X.]]
[[Category: Tu, X.]]
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[[Category: Aid]]
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[[Category: Azt]]
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[[Category: Azt resistance mechanism]]
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[[Category: Azt resistance mutation]]
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[[Category: Aztp4a]]
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[[Category: Aztppppa]]
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[[Category: Dinucleoside tetraphosphate]]
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[[Category: Dna polymerase]]
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[[Category: Dna-directed dna polymerase]]
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[[Category: Endonuclease]]
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[[Category: Hiv]]
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[[Category: Hiv-1 reverse transcriptase]]
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[[Category: Hydrolase]]
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[[Category: Magnesium]]
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[[Category: Metal-binding]]
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[[Category: Multifunctional enzyme]]
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[[Category: Nrti]]
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[[Category: Nrti resistance]]
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[[Category: Nuceleoside inhibitor]]
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[[Category: Nuclease]]
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[[Category: P51/p66]]
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[[Category: Rna-directed dna polymerase]]
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[[Category: Thymidine analog mutation]]
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[[Category: Transferase]]
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[[Category: Transferase-dna complex]]
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[[Category: Wild-type]]

Revision as of 22:20, 25 July 2012

Image:3klf.png

Template:STRUCTURE 3klf

Contents

Crystal structure of wild-type HIV-1 Reverse Transcriptase crosslinked to a DSDNA with a bound excision product, AZTPPPPA

Template:ABSTRACT PUBMED 20852643

About this Structure

3klf is a 16 chain structure of Reverse transcriptase with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

See Also

Reference

  • Tu X, Das K, Han Q, Bauman JD, Clark AD Jr, Hou X, Frenkel YV, Gaffney BL, Jones RA, Boyer PL, Hughes SH, Sarafianos SG, Arnold E. Structural basis of HIV-1 resistance to AZT by excision. Nat Struct Mol Biol. 2010 Oct;17(10):1202-9. Epub 2010 Sep 19. PMID:20852643 doi:10.1038/nsmb.1908

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OCA

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