3kli

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[[Image:3kli.png|left|200px]]
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{{STRUCTURE_3kli| PDB=3kli | SCENE= }}
{{STRUCTURE_3kli| PDB=3kli | SCENE= }}
===Crystal structure of unliganded AZT-resistant HIV-1 Reverse Transcriptase===
===Crystal structure of unliganded AZT-resistant HIV-1 Reverse Transcriptase===
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{{ABSTRACT_PUBMED_20852643}}
{{ABSTRACT_PUBMED_20852643}}
==About this Structure==
==About this Structure==
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[[3kli]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KLI OCA].
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[[3kli]] is a 2 chain structure of [[AZT-resistant HIV-1 reverse transcriptase]] and [[Reverse transcriptase]] with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KLI OCA].
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==See Also==
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*[[AZT-resistant HIV-1 reverse transcriptase|AZT-resistant HIV-1 reverse transcriptase]]
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*[[Reverse transcriptase|Reverse transcriptase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:20852643</ref><references group="xtra"/>
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<ref group="xtra">PMID:020852643</ref><references group="xtra"/>
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Arnold, E.]]
[[Category: Arnold, E.]]
[[Category: Sarafianos, S G.]]
[[Category: Sarafianos, S G.]]
[[Category: Tu, X.]]
[[Category: Tu, X.]]
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[[Category: Aid]]
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[[Category: Azt]]
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[[Category: Azt resistance]]
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[[Category: Azt resistance mechanism]]
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[[Category: Azt resistance mutation]]
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[[Category: Dna polymerase]]
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[[Category: Dna recombination]]
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[[Category: Hetero dimer]]
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[[Category: Hiv]]
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[[Category: Multifunctional enzyme]]
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[[Category: Nrti]]
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[[Category: Nucleoside inhibitor]]
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[[Category: P51/p66]]
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[[Category: Reverse transcriptase]]
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[[Category: Rna-directed dna polymerase]]
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[[Category: Transferase]]

Revision as of 05:25, 27 July 2012


PDB ID 3kli

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3kli, resolution 2.65Å ()
Gene: gag-pol (Human immunodeficiency virus 1)
Related: 3kle, 3klf, 3klg, 3klh


Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



Contents

Crystal structure of unliganded AZT-resistant HIV-1 Reverse Transcriptase

Template:ABSTRACT PUBMED 20852643

About this Structure

3kli is a 2 chain structure of AZT-resistant HIV-1 reverse transcriptase and Reverse transcriptase with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

See Also

Reference

  • Tu X, Das K, Han Q, Bauman JD, Clark AD Jr, Hou X, Frenkel YV, Gaffney BL, Jones RA, Boyer PL, Hughes SH, Sarafianos SG, Arnold E. Structural basis of HIV-1 resistance to AZT by excision. Nat Struct Mol Biol. 2010 Oct;17(10):1202-9. Epub 2010 Sep 19. PMID:20852643 doi:10.1038/nsmb.1908

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