3mcv

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[[Image:3mcv.png|left|200px]]
 
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{{STRUCTURE_3mcv| PDB=3mcv | SCENE= }}
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===Structure of PTR1 from Trypanosoma brucei in ternary complex with 2,4-diamino-5-[2-(2,5-dimethoxyphenyl)ethyl]thieno[2,3-d]-pyrimidine and NADP+===
===Structure of PTR1 from Trypanosoma brucei in ternary complex with 2,4-diamino-5-[2-(2,5-dimethoxyphenyl)ethyl]thieno[2,3-d]-pyrimidine and NADP+===
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==Reference==
==Reference==
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<ref group="xtra">PMID:21123874</ref><references group="xtra"/>
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<ref group="xtra">PMID:021123874</ref><references group="xtra"/><references/>
[[Category: Pteridine reductase]]
[[Category: Pteridine reductase]]
[[Category: Trypanosoma brucei brucei]]
[[Category: Trypanosoma brucei brucei]]
[[Category: Hunter, W N.]]
[[Category: Hunter, W N.]]
[[Category: Tulloch, L B.]]
[[Category: Tulloch, L B.]]
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[[Category: Antifolate]]
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[[Category: Oxidoreductase]]
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[[Category: Pteridine reductase]]

Revision as of 23:16, 10 April 2013

Template:STRUCTURE 3mcv

Structure of PTR1 from Trypanosoma brucei in ternary complex with 2,4-diamino-5-[2-(2,5-dimethoxyphenyl)ethyl]thieno[2,3-d]-pyrimidine and NADP+

Template:ABSTRACT PUBMED 21123874

About this Structure

3mcv is a 4 chain structure with sequence from Trypanosoma brucei brucei. Full crystallographic information is available from OCA.

Reference

  • Dawson A, Tulloch LB, Barrack KL, Hunter WN. High-resolution structures of Trypanosoma brucei pteridine reductase ligand complexes inform on the placement of new molecular entities in the active site of a potential drug target. Acta Crystallogr D Biol Crystallogr. 2010 Dec;66(Pt 12):1334-40. Epub 2010, Nov 16. PMID:21123874 doi:10.1107/S0907444910040886

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