3nbk

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[[Image:3nbk.png|left|200px]]
 
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{{STRUCTURE_3nbk| PDB=3nbk | SCENE= }}
{{STRUCTURE_3nbk| PDB=3nbk | SCENE= }}
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===Phosphopantetheine Adenylyltransferase from Mycobacterium tuberculosis in complex with 4'-phosphopantetheine===
===Phosphopantetheine Adenylyltransferase from Mycobacterium tuberculosis in complex with 4'-phosphopantetheine===
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{{ABSTRACT_PUBMED_20851704}}
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==Function==
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[[http://www.uniprot.org/uniprot/COAD_MYCTU COAD_MYCTU]] Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity).
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(as it appears on PubMed at http://www.pubmed.gov), where 20851704 is the PubMed ID number.
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{{ABSTRACT_PUBMED_20851704}}
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==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:20851704</ref><references group="xtra"/>
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<ref group="xtra">PMID:020851704</ref><references group="xtra"/><references/>
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Pantetheine-phosphate adenylyltransferase]]
[[Category: Pantetheine-phosphate adenylyltransferase]]
[[Category: Mesecar, A D.]]
[[Category: Mesecar, A D.]]
[[Category: Wubben, T J.]]
[[Category: Wubben, T J.]]
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[[Category: Pantetheine]]
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[[Category: Phosphopantetheine adenylyltransferase]]
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[[Category: Php]]
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[[Category: Ppat]]
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[[Category: Transferase]]
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[[Category: Tuberculosis]]

Revision as of 20:46, 17 April 2013

Template:STRUCTURE 3nbk

Contents

Phosphopantetheine Adenylyltransferase from Mycobacterium tuberculosis in complex with 4'-phosphopantetheine

Template:ABSTRACT PUBMED 20851704

Function

[COAD_MYCTU] Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity).

About this Structure

3nbk is a 4 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

Reference

  • Wubben TJ, Mesecar AD. Kinetic, thermodynamic, and structural insight into the mechanism of phosphopantetheine adenylyltransferase from Mycobacterium tuberculosis. J Mol Biol. 2010 Nov 26;404(2):202-19. Epub 2010 Sep 21. PMID:20851704 doi:10.1016/j.jmb.2010.09.002

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OCA

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