3pdj

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m (Protected "3pdj" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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[[Image:3pdj.jpg|left|200px]]
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The entry 3pdj is ON HOLD until Paper Publication
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{{STRUCTURE_3pdj| PDB=3pdj | SCENE= }}
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Authors: Wang, Z., Sudom, A., Walker, N.P.
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===Crystal Structure of Human 11-beta-Hydroxysteroid Dehydrogenase 1 (11b-HSD1) in Complex with 4,4-Disubstituted Cyclohexylbenzamide Inhibitor===
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Description: Crystal Structure of Human 11-beta-Hydroxysteroid Dehydrogenase 1 (11b-HSD1) in Complex with 4,4-Disubstituted Cyclohexylbenzamide Inhibitor
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{{ABSTRACT_PUBMED_21093258}}
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==About this Structure==
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[[3pdj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PDJ OCA].
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==Reference==
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<ref group="xtra">PMID:021093258</ref><references group="xtra"/>
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[[Category: 11-beta-hydroxysteroid dehydrogenase]]
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[[Category: Homo sapiens]]
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[[Category: Sudom, A.]]
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[[Category: Walker, N P.]]
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[[Category: Wang, Z.]]
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[[Category: 11beta]]
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[[Category: Dehydrogenase]]
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[[Category: Hydroxysteroid]]
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[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]

Revision as of 06:33, 5 October 2011

Image:3pdj.jpg

Template:STRUCTURE 3pdj

Crystal Structure of Human 11-beta-Hydroxysteroid Dehydrogenase 1 (11b-HSD1) in Complex with 4,4-Disubstituted Cyclohexylbenzamide Inhibitor

Template:ABSTRACT PUBMED 21093258

About this Structure

3pdj is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Sun D, Wang Z, Caille S, DeGraffenreid M, Gonzalez-Lopez de Turiso F, Hungate R, Jaen JC, Jiang B, Julian LD, Kelly R, McMinn DL, Kaizerman J, Rew Y, Sudom A, Tu H, Ursu S, Walker N, Willcockson M, Yan X, Ye Q, Powers JP. Synthesis and optimization of novel 4,4-disubstituted cyclohexylbenzamide derivatives as potent 11beta-HSD1 inhibitors. Bioorg Med Chem Lett. 2011 Jan 1;21(1):405-10. Epub 2010 Oct 31. PMID:21093258 doi:10.1016/j.bmcl.2010.10.129

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OCA

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