3nlt

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[[Image:3nlt.jpg|left|200px]]
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{{STRUCTURE_3nlt| PDB=3nlt | SCENE= }}
{{STRUCTURE_3nlt| PDB=3nlt | SCENE= }}
===Structure of endothelial nitric oxide synthase heme domain complexed with N1-{(3'S,4'S)-4'-[(6"-amino-4"-methylpyridin-2"-yl)methyl]pyrrolidin-3'-yl}- N2-(3'-fluorophenethyl)ethane-1,2-diamine tetrahydrochloride===
===Structure of endothelial nitric oxide synthase heme domain complexed with N1-{(3'S,4'S)-4'-[(6"-amino-4"-methylpyridin-2"-yl)methyl]pyrrolidin-3'-yl}- N2-(3'-fluorophenethyl)ethane-1,2-diamine tetrahydrochloride===
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{{ABSTRACT_PUBMED_20843082}}
{{ABSTRACT_PUBMED_20843082}}
==About this Structure==
==About this Structure==
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[[3nlt]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NLT OCA].
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[[3nlt]] is a 2 chain structure of [[Nitric Oxide Synthase]] with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NLT OCA].
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==See Also==
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*[[Nitric Oxide Synthase|Nitric Oxide Synthase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:20843082</ref><references group="xtra"/>
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<ref group="xtra">PMID:020843082</ref><references group="xtra"/>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Nitric-oxide synthase]]
[[Category: Nitric-oxide synthase]]
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[[Category: Silverman, R B.]]
[[Category: Silverman, R B.]]
[[Category: Xue, F.]]
[[Category: Xue, F.]]
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[[Category: Heme enzyme]]
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[[Category: Nitric oxide synthase]]
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[[Category: Oxidoreductase]]
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[[Category: Substrate inhibitor]]

Revision as of 20:33, 25 July 2012

Template:STRUCTURE 3nlt

Contents

Structure of endothelial nitric oxide synthase heme domain complexed with N1-{(3'S,4'S)-4'-[(6"-amino-4"-methylpyridin-2"-yl)methyl]pyrrolidin-3'-yl}- N2-(3'-fluorophenethyl)ethane-1,2-diamine tetrahydrochloride

Template:ABSTRACT PUBMED 20843082

About this Structure

3nlt is a 2 chain structure of Nitric Oxide Synthase with sequence from Bos taurus. Full crystallographic information is available from OCA.

See Also

Reference

  • Xue F, Li H, Delker SL, Fang J, Martasek P, Roman LJ, Poulos TL, Silverman RB. Potent, highly selective, and orally bioavailable gem-difluorinated monocationic inhibitors of neuronal nitric oxide synthase. J Am Chem Soc. 2010 Oct 13;132(40):14229-38. PMID:20843082 doi:10.1021/ja106175q

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