3q6w

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[[Image:3q6w.jpg|left|200px]]
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===Structure of dually-phosphorylated MET receptor kinase in complex with an MK-2461 analog with specificity for the activated receptor===
===Structure of dually-phosphorylated MET receptor kinase in complex with an MK-2461 analog with specificity for the activated receptor===
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The line below this paragraph, {{ABSTRACT_PUBMED_21247903}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 21247903 is the PubMed ID number.
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{{ABSTRACT_PUBMED_21247903}}
==About this Structure==
==About this Structure==
[[3q6w]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q6W OCA].
[[3q6w]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q6W OCA].
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==Reference==
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<ref group="xtra">PMID:021247903</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
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[[Category: Rickert, K W.]]
[[Category: Rickert, K W.]]
[[Category: Soisson, S M.]]
[[Category: Soisson, S M.]]
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[[Category: Transferase-transferase inhibitor complex]]
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[[Category: Two phosphotyrosine resiude]]
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[[Category: Tyrosine kinase]]

Revision as of 16:00, 22 June 2011

Template:STRUCTURE 3q6w

Structure of dually-phosphorylated MET receptor kinase in complex with an MK-2461 analog with specificity for the activated receptor

Template:ABSTRACT PUBMED 21247903

About this Structure

3q6w is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Rickert KW, Patel SB, Allison TJ, Byrne NJ, Darke PL, Ford RE, Guerin DJ, Hall DL, Kornienko M, Lu J, Munshi SK, Reid JC, Shipman JM, Stanton EF, Wilson KJ, Young JR, Soisson SM, Lumb KJ. Structural basis for selective small molecule kinase inhibition of activated c-Met. J Biol Chem. 2011 Apr 1;286(13):11218-25. Epub 2011 Jan 18. PMID:21247903 doi:10.1074/jbc.M110.204404

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