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3ll6
From Proteopedia
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{{STRUCTURE_3ll6| PDB=3ll6 | SCENE= }} | {{STRUCTURE_3ll6| PDB=3ll6 | SCENE= }} | ||
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===Crystal structure of the human cyclin G associated kinase (GAK)=== | ===Crystal structure of the human cyclin G associated kinase (GAK)=== | ||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/GAK_HUMAN GAK_HUMAN]] Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1.<ref>PMID:10625686</ref> | ||
==About this Structure== | ==About this Structure== | ||
[[3ll6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LL6 OCA]. | [[3ll6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LL6 OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
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[[Category: Weigelt, J.]] | [[Category: Weigelt, J.]] | ||
[[Category: Zhang, R.]] | [[Category: Zhang, R.]] | ||
| + | [[Category: Atp-binding]] | ||
| + | [[Category: Cell cycle]] | ||
| + | [[Category: Cell junction]] | ||
| + | [[Category: Clathrine]] | ||
| + | [[Category: Cyclin g]] | ||
| + | [[Category: Golgi apparatus]] | ||
| + | [[Category: Kinase]] | ||
| + | [[Category: Mcsg]] | ||
| + | [[Category: Membrane trafficking]] | ||
| + | [[Category: Midwest center for structural genomic]] | ||
| + | [[Category: Nucleotide-binding]] | ||
| + | [[Category: P53]] | ||
| + | [[Category: Phosphoprotein]] | ||
| + | [[Category: Protein kinase]] | ||
| + | [[Category: Protein structure initiative]] | ||
| + | [[Category: Psi-2]] | ||
| + | [[Category: Serine/threonine kinase]] | ||
| + | [[Category: Serine/threonine-protein kinase]] | ||
| + | [[Category: Sgc]] | ||
| + | [[Category: Structural genomic]] | ||
| + | [[Category: Structural genomics consortium]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 20:44, 4 April 2013
Contents |
Crystal structure of the human cyclin G associated kinase (GAK)
Function
[GAK_HUMAN] Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1.[1]
About this Structure
3ll6 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- ↑ Greener T, Zhao X, Nojima H, Eisenberg E, Greene LE. Role of cyclin G-associated kinase in uncoating clathrin-coated vesicles from non-neuronal cells. J Biol Chem. 2000 Jan 14;275(2):1365-70. PMID:10625686
Categories: Homo sapiens | Non-specific serine/threonine protein kinase | Arrowsmith, C H. | Bountra, C. | Delft, F Von. | Edwards, A. | Eswaran, J. | Fedorov, O. | Hatzos-Skintges, C. | Joachimiak, A. | King, O. | Knapp, S. | MCSG, Midwest Center for Structural Genomics. | SGC, Structural Genomics Consortium. | Weger, A. | Weigelt, J. | Zhang, R. | Atp-binding | Cell cycle | Cell junction | Clathrine | Cyclin g | Golgi apparatus | Kinase | Mcsg | Membrane trafficking | Midwest center for structural genomic | Nucleotide-binding | P53 | Phosphoprotein | Protein kinase | Protein structure initiative | Psi-2 | Serine/threonine kinase | Serine/threonine-protein kinase | Sgc | Structural genomic | Structural genomics consortium | Transferase
