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3po8

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[[Image:3po8.jpg|left|200px]]
 
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{{STRUCTURE_3po8| PDB=3po8 | SCENE= }}
{{STRUCTURE_3po8| PDB=3po8 | SCENE= }}
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===Structural and functional analysis of phosphothreonine-dependent FHA domain interactions===
===Structural and functional analysis of phosphothreonine-dependent FHA domain interactions===
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{{ABSTRACT_PUBMED_21134638}}
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==Function==
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[[http://www.uniprot.org/uniprot/P71590_MYCTU P71590_MYCTU]] Regulates cell growth and peptidoglycan synthesis by binding to MviN. May inhibit the late stages of peptidoglycan synthesis.<ref>PMID:22275220</ref>
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{{ABSTRACT_PUBMED_21134638}}
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==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:21134638</ref><references group="xtra"/>
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<ref group="xtra">PMID:021134638</ref><references group="xtra"/><references/>
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Pennell, S.]]
[[Category: Pennell, S.]]
[[Category: Smerdon, S J.]]
[[Category: Smerdon, S J.]]
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[[Category: Fha domain]]
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[[Category: Peptide binding protein]]
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[[Category: Synthetic peptide]]

Revision as of 08:10, 8 May 2013

Template:STRUCTURE 3po8

Contents

Structural and functional analysis of phosphothreonine-dependent FHA domain interactions

Template:ABSTRACT PUBMED 21134638

Function

[P71590_MYCTU] Regulates cell growth and peptidoglycan synthesis by binding to MviN. May inhibit the late stages of peptidoglycan synthesis.[1]

About this Structure

3po8 is a 1 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

Reference

  • Pennell S, Westcott S, Ortiz-Lombardia M, Patel D, Li J, Nott TJ, Mohammed D, Buxton RS, Yaffe MB, Verma C, Smerdon SJ. Structural and functional analysis of phosphothreonine-dependent FHA domain interactions. Structure. 2010 Dec 8;18(12):1587-95. PMID:21134638 doi:10.1016/j.str.2010.09.014
  1. ↑ Gee CL, Papavinasasundaram KG, Blair SR, Baer CE, Falick AM, King DS, Griffin JE, Venghatakrishnan H, Zukauskas A, Wei JR, Dhiman RK, Crick DC, Rubin EJ, Sassetti CM, Alber T. A phosphorylated pseudokinase complex controls cell wall synthesis in mycobacteria. Sci Signal. 2012 Jan 24;5(208):ra7. PMID:22275220 doi:10.1126/scisignal.2002525

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