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3q0c
From Proteopedia
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{{STRUCTURE_3q0c| PDB=3q0c | SCENE= }} | {{STRUCTURE_3q0c| PDB=3q0c | SCENE= }} | ||
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===Crystal structure of SUVH5 SRA-fully methylated CG DNA complex in space group P6122=== | ===Crystal structure of SUVH5 SRA-fully methylated CG DNA complex in space group P6122=== | ||
| + | {{ABSTRACT_PUBMED_21245167}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/SUVH5_ARATH SUVH5_ARATH]] Histone methyltransferase. Methylates 'Lys-9' of histone H3. H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression. | |
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==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:021245167</ref><references group="xtra"/><references/> |
[[Category: Arabidopsis thaliana]] | [[Category: Arabidopsis thaliana]] | ||
[[Category: Histone-lysine N-methyltransferase]] | [[Category: Histone-lysine N-methyltransferase]] | ||
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[[Category: Patel, D J.]] | [[Category: Patel, D J.]] | ||
[[Category: Simanshu, D K.]] | [[Category: Simanshu, D K.]] | ||
| + | [[Category: 5mc binding protein]] | ||
| + | [[Category: Fully methylated cg]] | ||
| + | [[Category: Fully methylated cg dna duplex]] | ||
| + | [[Category: Sra]] | ||
| + | [[Category: Suvh5]] | ||
| + | [[Category: Transferase-dna complex]] | ||
Revision as of 08:33, 8 May 2013
Contents |
Crystal structure of SUVH5 SRA-fully methylated CG DNA complex in space group P6122
Template:ABSTRACT PUBMED 21245167
Function
[SUVH5_ARATH] Histone methyltransferase. Methylates 'Lys-9' of histone H3. H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression.
About this Structure
3q0c is a 4 chain structure with sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA.
Reference
- Rajakumara E, Law JA, Simanshu DK, Voigt P, Johnson LM, Reinberg D, Patel DJ, Jacobsen SE. A dual flip-out mechanism for 5mC recognition by the Arabidopsis SUVH5 SRA domain and its impact on DNA methylation and H3K9 dimethylation in vivo. Genes Dev. 2011 Jan 15;25(2):137-52. PMID:21245167 doi:10.1101/gad.1980311
