3ps6

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[[Image:3ps6.png|left|200px]]
[[Image:3ps6.png|left|200px]]
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{{STRUCTURE_3ps6| PDB=3ps6 | SCENE= }}
{{STRUCTURE_3ps6| PDB=3ps6 | SCENE= }}
===Quinazolines with intra-molecular hydrogen bonding scaffold (iMHBS) as PI3K/mTOR dual inhibitors.===
===Quinazolines with intra-molecular hydrogen bonding scaffold (iMHBS) as PI3K/mTOR dual inhibitors.===
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{{ABSTRACT_PUBMED_21269826}}
{{ABSTRACT_PUBMED_21269826}}
==About this Structure==
==About this Structure==
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[[3ps6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PS6 OCA].
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[[3ps6]] is a 1 chain structure of [[Phosphoinositide 3-Kinases]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PS6 OCA].
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==See Also==
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*[[Phosphoinositide 3-Kinases|Phosphoinositide 3-Kinases]]
==Reference==
==Reference==
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<ref group="xtra">PMID:21269826</ref><references group="xtra"/>
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<ref group="xtra">PMID:021269826</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Phosphatidylinositol-4,5-bisphosphate 3-kinase]]
[[Category: Phosphatidylinositol-4,5-bisphosphate 3-kinase]]
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[[Category: Knighton, D R.]]
[[Category: Knighton, D R.]]
[[Category: Rogers, C M.L]]
[[Category: Rogers, C M.L]]
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[[Category: Phosphoinositide kinase]]
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[[Category: Transferase-transferase inhibitor complex]]

Revision as of 04:50, 27 July 2012

Template:STRUCTURE 3ps6

Contents

Quinazolines with intra-molecular hydrogen bonding scaffold (iMHBS) as PI3K/mTOR dual inhibitors.

Template:ABSTRACT PUBMED 21269826

About this Structure

3ps6 is a 1 chain structure of Phosphoinositide 3-Kinases with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Liu KK, Huang X, Bagrodia S, Chen JH, Greasley S, Cheng H, Sun S, Knighton D, Rodgers C, Rafidi K, Zou A, Xiao J, Yan S. Quinazolines with intra-molecular hydrogen bonding scaffold (iMHBS) as PI3K/mTOR dual inhibitors. Bioorg Med Chem Lett. 2011 Feb 15;21(4):1270-4. Epub 2010 Dec 10. PMID:21269826 doi:10.1016/j.bmcl.2010.12.026

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