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3mzs
From Proteopedia
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{{STRUCTURE_3mzs| PDB=3mzs | SCENE= }} | {{STRUCTURE_3mzs| PDB=3mzs | SCENE= }} | ||
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===Crystal Structure of Cytochrome P450 CYP11A1 in complex with 22-hydroxy-cholesterol=== | ===Crystal Structure of Cytochrome P450 CYP11A1 in complex with 22-hydroxy-cholesterol=== | ||
| + | {{ABSTRACT_PUBMED_21159775}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/CP11A_BOVIN CP11A_BOVIN]] Catalyzes the side-chain cleavage reaction of cholesterol to pregnenolone. | |
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==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:021159775</ref><references group="xtra"/><references/> |
[[Category: Bos taurus]] | [[Category: Bos taurus]] | ||
[[Category: Annalora, A.]] | [[Category: Annalora, A.]] | ||
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[[Category: Pikuleva, I.]] | [[Category: Pikuleva, I.]] | ||
[[Category: Stout, C D.]] | [[Category: Stout, C D.]] | ||
| + | [[Category: Cholesterol]] | ||
| + | [[Category: Cholesterol 20-22-desmolase]] | ||
| + | [[Category: Cyp11a1]] | ||
| + | [[Category: Cytochrome p450]] | ||
| + | [[Category: Heme]] | ||
| + | [[Category: Monooxygenase]] | ||
| + | [[Category: Oxidoreductase]] | ||
| + | [[Category: Side chain cleavage enzyme]] | ||
| + | [[Category: Steroid metabolism]] | ||
Revision as of 20:58, 17 April 2013
Contents |
Crystal Structure of Cytochrome P450 CYP11A1 in complex with 22-hydroxy-cholesterol
Template:ABSTRACT PUBMED 21159775
Function
[CP11A_BOVIN] Catalyzes the side-chain cleavage reaction of cholesterol to pregnenolone.
About this Structure
3mzs is a 4 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.
Reference
- Mast N, Annalora AJ, Lodowski DT, Palczewski K, Stout CD, Pikuleva IA. Structural basis for three-step sequential catalysis by the cholesterol side chain cleavage enzyme CYP11A1. J Biol Chem. 2010 Dec 15. PMID:21159775 doi:10.1074/jbc.M110.188433
