3qjz

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'''Unreleased structure'''
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[[Image:3qjz.jpg|left|200px]]
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The entry 3qjz is ON HOLD until Paper Publication
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{{STRUCTURE_3qjz| PDB=3qjz | SCENE= }}
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Authors: Whittington, D.A., Tang, J., Yakowec, P.
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===Crystal structure of PI3K-gamma in complex with benzothiazole 1===
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Description: Crystal structure of PI3K-gamma in complex with benzothiazole 1
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{{ABSTRACT_PUBMED_21332118}}
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==About this Structure==
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[[3qjz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QJZ OCA].
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==Reference==
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<ref group="xtra">PMID:21332118</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Phosphatidylinositol-4,5-bisphosphate 3-kinase]]
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[[Category: Tang, J.]]
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[[Category: Whittington, D A.]]
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[[Category: Yakowec, P.]]

Revision as of 08:02, 30 March 2011

Template:STRUCTURE 3qjz

Crystal structure of PI3K-gamma in complex with benzothiazole 1

Template:ABSTRACT PUBMED 21332118

About this Structure

3qjz is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • D'Angelo ND, Kim TS, Andrews K, Booker SK, Caenepeel S, Chen K, D'Amico D, Freeman D, Jiang J, Liu L, McCarter JD, San Miguel T, Mullady EL, Schrag M, Subramanian R, Tang J, Wahl RC, Wang L, Whittington DA, Wu T, Xi N, Xu Y, Yakowec P, Yang K, Zalameda LP, Zhang N, Hughes P, Norman MH. Discovery and Optimization of a Series of Benzothiazole Phosphoinositide 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Dual Inhibitors. J Med Chem. 2011 Mar 24;54(6):1789-811. Epub 2011 Feb 18. PMID:21332118 doi:10.1021/jm1014605

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