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Human thymidylate synthase is in the closed conformation when complexed with dUMP and raltitrexed, an antifolate drug.<ref name="Phan">11329255</ref> [http://en.wikipedia.org/wiki/Thymidylate_synthase Wikipedia] | Human thymidylate synthase is in the closed conformation when complexed with dUMP and raltitrexed, an antifolate drug.<ref name="Phan">11329255</ref> [http://en.wikipedia.org/wiki/Thymidylate_synthase Wikipedia] | ||
| + | ==Biochemistry== | ||
Revision as of 23:07, 3 March 2011
| This Sandbox is Reserved from January 10, 2010, through April 10, 2011 for use in BCMB 307-Proteins course taught by Andrea Gorrell at the University of Northern British Columbia, Prince George, BC, Canada. |
To get started:
More help: Help:Editing |
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| 1hvy, resolution 1.90Å () | |||||||||
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| Ligands: | , , | ||||||||
| Non-Standard Residues: | |||||||||
| Activity: | Thymidylate synthase, with EC number 2.1.1.45 | ||||||||
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| Resources: | FirstGlance, OCA, RCSB, PDBsum | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
Overview
Human thymidylate synthase is in the closed conformation when complexed with dUMP and raltitrexed, an antifolate drug.[1] Wikipedia
