Proliferating Cell Nuclear Antigen
From Proteopedia
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[[3lx2]] - TkPCNA2<br /> | [[3lx2]] - TkPCNA2<br /> | ||
[[3lox]], [[1plq]], [[1plr]] – yPCNA - yeast<br /> | [[3lox]], [[1plq]], [[1plr]] – yPCNA - yeast<br /> | ||
| + | [[3f1x]], [[3gpm]], [[3gpn]] - yPCNA (mutant)<br /> | ||
| + | [[3l0x]] - yPCNA N fragment + C fragment<br /> | ||
| + | [[3gpe]] - yPCNA N fragment + SUMO-C fragment<br /> | ||
[[1vym]], [[1w60]] – hPCNA - human<br /> | [[1vym]], [[1w60]] – hPCNA - human<br /> | ||
[[2io4]] – SsPCNA B (mutant) + PCNA C - ''Sulfolobus solfataricus''<br /> | [[2io4]] – SsPCNA B (mutant) + PCNA C - ''Sulfolobus solfataricus''<br /> | ||
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[[2ijx]] - SsPCNA A<br /> | [[2ijx]] - SsPCNA A<br /> | ||
[[1iz4]], [[1iz5]] – PfPCNA (mutant) - ''Pyrococcus furiosus''<br /> | [[1iz4]], [[1iz5]] – PfPCNA (mutant) - ''Pyrococcus furiosus''<br /> | ||
| + | [[3hi8]], [[3ifv]] - PCNA - ''Haloferax volcanii'' | ||
===PCNA + Dpo=== | ===PCNA + Dpo=== | ||
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[[1vyj]], [[1u76]], [[1u7b]] – hPCNA + peptide<br /> | [[1vyj]], [[1u76]], [[1u7b]] – hPCNA + peptide<br /> | ||
| - | [[3p83]] - AfPCNA + RNase | + | [[1axc]] - hPCNA + P21/WAF1 C-terminat<br /> |
| - | [[1rxm]] – AfPCNA + | + | [[1ul1]] - hPCNA + Flap exonuclease-1<br /> |
| + | [[3p87]] - hPCNA + RNase H2 subunit B (mutant)<br /> | ||
| + | [[3p83]] - AfPCNA + RNase H2<br /> | ||
| + | [[1rxm]] – AfPCNA + Flap exonuclease-1 peptide<br /> | ||
[[1rxz]] - AfPCNA + Flap structure-specific endonuclease<br /> | [[1rxz]] - AfPCNA + Flap structure-specific endonuclease<br /> | ||
[[3l0w]], [[3l10]] - yPCNA + monoubiquinated PCNA<br /> | [[3l0w]], [[3l10]] - yPCNA + monoubiquinated PCNA<br /> | ||
[[1sxj]] – yPCNA + replication factor C<br /> | [[1sxj]] – yPCNA + replication factor C<br /> | ||
| + | [[2od8]] - yPCNA + DNA ligase fragment<br /> | ||
| + | [[3k4x]] - yPCNA + DNA<br /> | ||
[[2izo]] - SsPCNA B + PCNA C + Flap structure-specific endonuclease<br /> | [[2izo]] - SsPCNA B + PCNA C + Flap structure-specific endonuclease<br /> | ||
[[1isq]] - PfPCNA (mutant) + replication factor C large subunit<br /> | [[1isq]] - PfPCNA (mutant) + replication factor C large subunit<br /> | ||
| + | [[2zvw]] - PCNA + cyclin-dependent kinase inhibitor 1 - ''Arabidopsis thaliana''<br /> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 08:49, 22 March 2011
Proliferating Cell Nuclear Antigen (PCNA) acts as a DNA sliding clamp by encircling the DNA and linking it to the genome. It is a processivity factor for DNA polymerase (Dpo) δ in eukaryotic cells. The images at the left and at the right correspond to one representative PCNA, i.e. the crystal structure of Proliferating Cell Nuclear Antigen from Archaeglobus fulgidus (1rwz).
Contents |
3D Structures of Proliferating Cell Nuclear Antigen
Unliganded PCNA
1rwz – AfPCNA - Archaeglobus fulgidus
3lx1 - TkPCNA1 - Thermococcus kodakarensis
3lx2 - TkPCNA2
3lox, 1plq, 1plr – yPCNA - yeast
3f1x, 3gpm, 3gpn - yPCNA (mutant)
3l0x - yPCNA N fragment + C fragment
3gpe - yPCNA N fragment + SUMO-C fragment
1vym, 1w60 – hPCNA - human
2io4 – SsPCNA B (mutant) + PCNA C - Sulfolobus solfataricus
2hii, 2hik, 2ixi - SsPCNA A + PCNA B + PCNA C
2nti - SsPCNA A + PCNA B (mutant) + PCNA C
2ijx - SsPCNA A
1iz4, 1iz5 – PfPCNA (mutant) - Pyrococcus furiosus
3hi8, 3ifv - PCNA - Haloferax volcanii
PCNA + Dpo
2zvk – hPCNA + hDpo ε
2zvl – hPCNA + hDpo κ
2zvm – hPCNA + hDpo τ
3fds – SsPCNA B + PCNA C + SsDpo IV
3a2f - PfPCNA + Dpo
PCNA complexes
1vyj, 1u76, 1u7b – hPCNA + peptide
1axc - hPCNA + P21/WAF1 C-terminat
1ul1 - hPCNA + Flap exonuclease-1
3p87 - hPCNA + RNase H2 subunit B (mutant)
3p83 - AfPCNA + RNase H2
1rxm – AfPCNA + Flap exonuclease-1 peptide
1rxz - AfPCNA + Flap structure-specific endonuclease
3l0w, 3l10 - yPCNA + monoubiquinated PCNA
1sxj – yPCNA + replication factor C
2od8 - yPCNA + DNA ligase fragment
3k4x - yPCNA + DNA
2izo - SsPCNA B + PCNA C + Flap structure-specific endonuclease
1isq - PfPCNA (mutant) + replication factor C large subunit
2zvw - PCNA + cyclin-dependent kinase inhibitor 1 - Arabidopsis thaliana
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Alexander Berchansky, Lukáš Cakl, Joel L. Sussman
