Index.php/Sandbox Reserved 337
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | ==This is a placeholder== | ||
| - | This is a placeholder text to help you get started in | ||
| - | placing a Jmol applet on your page. At any time, click | ||
| - | "Show Preview" at the bottom of this page to see how it goes. | ||
| - | |||
| - | Replace the PDB id (use lowercase!) after the STRUCTURE_ and after PDB= to load | ||
| - | and display another structure. | ||
=Chorismate synthase= | =Chorismate synthase= | ||
{{STRUCTURE_1ztb | PDB=1ztb | SCENE=Index.php/Sandbox_Reserved_337/Aroc/1 }} | {{STRUCTURE_1ztb | PDB=1ztb | SCENE=Index.php/Sandbox_Reserved_337/Aroc/1 }} | ||
__TOC__ | __TOC__ | ||
| + | Chorismate Synthase is the last enzyme present in the shikimate pathway<ref name= "planta"> PMID:9951731</ref>, a process which converts phosphoenolpyruvate, and erythrose 4-phosphate to chorismate in a series of seven steps.<ref name= “review”> PMID:15012217</ref> The shikimate pathway is essential in the production of the amino acids phenylalanine, tryptophan and tyrosine, all essential amino acids.<ref name= "main"> PMID:16459102</ref> | ||
| + | |||
=Structure= | =Structure= | ||
==Function== | ==Function== | ||
| + | |||
=Pathway= | =Pathway= | ||
=References= | =References= | ||
| + | <references /> | ||
Revision as of 20:59, 14 March 2011
Chorismate synthase
| |||||||||
| 1ztb, resolution 2.65Å () | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Gene: | aroC, aroF (Mycobacterium tuberculosis) | ||||||||
| Activity: | Chorismate synthase, with EC number 4.2.3.5 | ||||||||
| |||||||||
| |||||||||
| |||||||||
| Resources: | FirstGlance, OCA, RCSB, PDBsum | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
Contents |
Chorismate Synthase is the last enzyme present in the shikimate pathway[1], a process which converts phosphoenolpyruvate, and erythrose 4-phosphate to chorismate in a series of seven steps.[2] The shikimate pathway is essential in the production of the amino acids phenylalanine, tryptophan and tyrosine, all essential amino acids.[3]
Structure
Function
Pathway
References
- ↑ Macheroux P, Schmid J, Amrhein N, Schaller A. A unique reaction in a common pathway: mechanism and function of chorismate synthase in the shikimate pathway. Planta. 1999 Jan;207(3):325-34. PMID:9951731
- ↑ Herrmann KM, Weaver LM. THE SHIKIMATE PATHWAY. Annu Rev Plant Physiol Plant Mol Biol. 1999 Jun;50:473-503. PMID:15012217 doi:10.1146/annurev.arplant.50.1.473
- ↑ Dias MV, Borges JC, Ely F, Pereira JH, Canduri F, Ramos CH, Frazzon J, Palma MS, Basso LA, Santos DS, de Azevedo WF Jr. Structure of chorismate synthase from Mycobacterium tuberculosis. J Struct Biol. 2006 May;154(2):130-43. Epub 2006 Jan 17. PMID:16459102 doi:10.1016/j.jsb.2005.12.008
