3pp1
From Proteopedia
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{{STRUCTURE_3pp1| PDB=3pp1 | SCENE= }} | {{STRUCTURE_3pp1| PDB=3pp1 | SCENE= }} | ||
===Crystal Structure of the Human Mitogen-activated protein kinase kinase 1 (MEK 1) in complex with ligand and MgATP=== | ===Crystal Structure of the Human Mitogen-activated protein kinase kinase 1 (MEK 1) in complex with ligand and MgATP=== | ||
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{{ABSTRACT_PUBMED_21310613}} | {{ABSTRACT_PUBMED_21310613}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3pp1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PP1 OCA]. | + | [[3pp1]] is a 1 chain structure of [[Mitogen-activated protein kinase kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PP1 OCA]. |
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| + | ==See Also== | ||
| + | *[[Mitogen-activated protein kinase kinase|Mitogen-activated protein kinase kinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:021310613</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Mitogen-activated protein kinase kinase]] | [[Category: Mitogen-activated protein kinase kinase]] | ||
[[Category: Dougan, D R.]] | [[Category: Dougan, D R.]] | ||
| + | [[Category: Atp binding]] | ||
| + | [[Category: Kinase]] | ||
| + | [[Category: Kinase domain]] | ||
| + | [[Category: Transferase-transferase inhibitor complex]] | ||
Revision as of 18:57, 26 July 2012
Contents |
Crystal Structure of the Human Mitogen-activated protein kinase kinase 1 (MEK 1) in complex with ligand and MgATP
Template:ABSTRACT PUBMED 21310613
About this Structure
3pp1 is a 1 chain structure of Mitogen-activated protein kinase kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Dong Q, Dougan DR, Gong X, Halkowycz P, Jin B, Kanouni T, O'Connell SM, Scorah N, Shi L, Wallace MB, Zhou F. Discovery of TAK-733, a potent and selective MEK allosteric site inhibitor for the treatment of cancer. Bioorg Med Chem Lett. 2011 Mar 1;21(5):1315-9. Epub 2011 Jan 22. PMID:21310613 doi:10.1016/j.bmcl.2011.01.071
