3ao5

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Revision as of 06:27, 9 March 2011

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Template:STRUCTURE 3ao5

Fragment-based approach to the design of ligands targeting a novel site on HIV-1 integrase

About this Structure

3ao5 is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

• Wielens J, Headey SJ, Deadman JJ, Rhodes DI, Parker MW, Chalmers DK, Scanlon MJ. Fragment-based design of ligands targeting a novel site on the integrase enzyme of human immunodeficiency virus 1. ChemMedChem. 2011 Feb 7;6(2):258-61. doi: 10.1002/cmdc.201000483. Epub, 2010 Dec 16. PMID:21275048 doi:10.1002/cmdc.201000483