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3l15

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Image:3l15.png

Template:STRUCTURE 3l15

Human Tead2 transcriptional factor

Template:ABSTRACT PUBMED 20368466

About this Structure

3l15 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Tian W, Yu J, Tomchick DR, Pan D, Luo X. Structural and functional analysis of the YAP-binding domain of human TEAD2. Proc Natl Acad Sci U S A. 2010 Apr 20;107(16):7293-8. Epub 2010 Apr 5. PMID:20368466
  • Wu S, Liu Y, Zheng Y, Dong J, Pan D. The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathway. Dev Cell. 2008 Mar;14(3):388-98. Epub 2008 Feb 7. PMID:18258486 doi:10.1016/j.devcel.2008.01.007
  • Chan SW, Lim CJ, Loo LS, Chong YF, Huang C, Hong W. TEADs mediate nuclear retention of TAZ to promote oncogenic transformation. J Biol Chem. 2009 May 22;284(21):14347-58. Epub 2009 Mar 26. PMID:19324876 doi:10.1074/jbc.M901568200
  • Zhao B, Ye X, Yu J, Li L, Li W, Li S, Yu J, Lin JD, Wang CY, Chinnaiyan AM, Lai ZC, Guan KL. TEAD mediates YAP-dependent gene induction and growth control. Genes Dev. 2008 Jul 15;22(14):1962-71. Epub 2008 Jun 25. PMID:18579750 doi:10.1101/gad.1664408

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