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1ol0

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Revision as of 18:24, 14 March 2011

Image:1ol0.png

Template:STRUCTURE 1ol0

CRYSTAL STRUCTURE OF A CAMELISED HUMAN VH

Template:ABSTRACT PUBMED 14730966

About this Structure

1ol0 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Dottorini T, Vaughan CK, Walsh MA, LoSurdo P, Sollazzo M. Crystal structure of a human VH: requirements for maintaining a monomeric fragment. Biochemistry. 2004 Jan 27;43(3):622-8. PMID:14730966 doi:10.1021/bi035800b
  • Di Marco S, Rizzi M, Volpari C, Walsh MA, Narjes F, Colarusso S, De Francesco R, Matassa VG, Sollazzo M. Inhibition of the hepatitis C virus NS3/4A protease. The crystal structures of two protease-inhibitor complexes. J Biol Chem. 2000 Mar 10;275(10):7152-7. PMID:10702283
  • Martin F, Volpari C, Steinkuhler C, Dimasi N, Brunetti M, Biasiol G, Altamura S, Cortese R, De Francesco R, Sollazzo M. Affinity selection of a camelized V(H) domain antibody inhibitor of hepatitis C virus NS3 protease. Protein Eng. 1997 May;10(5):607-14. PMID:9215580
  • Riechmann L. Rearrangement of the former VL interface in the solution structure of a camelised, single antibody VH domain. J Mol Biol. 1996 Jun 28;259(5):957-69. PMID:8683598 doi:10.1006/jmbi.1996.0373

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OCA

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