1h7x
From Proteopedia
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[[Image:1h7x.png|left|200px]] | [[Image:1h7x.png|left|200px]] | ||
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===DIHYDROPYRIMIDINE DEHYDROGENASE (DPD) FROM PIG, TERNARY COMPLEX OF A MUTANT ENZYME (C671A), NADPH AND 5-FLUOROURACIL=== | ===DIHYDROPYRIMIDINE DEHYDROGENASE (DPD) FROM PIG, TERNARY COMPLEX OF A MUTANT ENZYME (C671A), NADPH AND 5-FLUOROURACIL=== | ||
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==Reference== | ==Reference== | ||
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[[Category: Sus scrofa]] | [[Category: Sus scrofa]] | ||
[[Category: Dobritzsch, D.]] | [[Category: Dobritzsch, D.]] | ||
Revision as of 09:40, 16 January 2013
DIHYDROPYRIMIDINE DEHYDROGENASE (DPD) FROM PIG, TERNARY COMPLEX OF A MUTANT ENZYME (C671A), NADPH AND 5-FLUOROURACIL
Template:ABSTRACT PUBMED 11179210
About this Structure
1h7x is a 4 chain structure with sequence from Sus scrofa. Full crystallographic information is available from OCA.
Reference
- Dobritzsch D, Schneider G, Schnackerz KD, Lindqvist Y. Crystal structure of dihydropyrimidine dehydrogenase, a major determinant of the pharmacokinetics of the anti-cancer drug 5-fluorouracil. EMBO J. 2001 Feb 15;20(4):650-60. PMID:11179210 doi:10.1093/emboj/20.4.650
- Dobritzsch D, Persson K, Schneider G, Lindqvist Y. Crystallization and preliminary X-ray study of pig liver dihydropyrimidine dehydrogenase. Acta Crystallogr D Biol Crystallogr. 2001 Jan;57(Pt 1):153-5. PMID:11134942
