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1yz8

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Template:STRUCTURE 1yz8

Solution structure of the k50 class homeodomain pitx2 bound to dna and implications for mutations that cause rieger syndrome

Template:ABSTRACT PUBMED 15895993

About this Structure

1yz8 is a 3 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

  • Chaney BA, Clark-Baldwin K, Dave V, Ma J, Rance M. Solution structure of the K50 class homeodomain PITX2 bound to DNA and implications for mutations that cause Rieger syndrome. Biochemistry. 2005 May 24;44(20):7497-511. PMID:15895993 doi:10.1021/bi0473253
  • Otting G, Qian YQ, Billeter M, Muller M, Affolter M, Gehring WJ, Wuthrich K. Protein--DNA contacts in the structure of a homeodomain--DNA complex determined by nuclear magnetic resonance spectroscopy in solution. EMBO J. 1990 Oct;9(10):3085-92. PMID:1976507

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